83948-53-2

Basic information

• Product Name: tert-Butyl 3-bromopropylcarbamate
• Synonyms: N-(TERT-BUTOXYCARBONYL)-3-BROMOPROPYLAMINE;N-(3-BROMOPROPYL)CARBAMIC ACID TERT-BUTYL ESTER;N-BOC-3-BROMOPROPYLAMINE;TERT-BUTYL N-(3-BROMOPROPYL)CARBAMATE;(3-BROMO-PROPYL)-CARBAMIC ACID TERT-BUTYL ESTER;3-(BOC-AMINO)PROPYL BROMIDE;3-(tert-Butoxycarbonylamino)propyl bromide;TERT-BUTYL 3-BROMOPROPYLCARBAMATE
• CAS NO: 83948-53-2
• Molecular Formula: C₈H₁₆BrNO₂
• Molecular Weight: 238.12
• Mol File: 83948-53-2.mol
• Article Data: 9

Chemical Properties

• Melting Point: 37-39 °C
• Boiling Point: 285.286 °C at 760 mmHg
• Flash Point: 126.337 °C
• Appearance: White/Low Melting Solid
• Density: 1.279 g/cm³
• Vapor Pressure: 0.003mmHg at 25°C
• Refractive Index: 1.473
• Storage Temp.: 2-8°C
• PKA: 12.48±0.46(Predicted)
• BRN: 4176344
• CAS DataBase Reference: tert-Butyl 3-bromopropylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-Butyl 3-bromopropylcarbamate(83948-53-2)
• EPA Substance Registry System: tert-Butyl 3-bromopropylcarbamate(83948-53-2)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26-24/25
• WGK Germany: 3
• F: 10-21
• Hazardous Substances Data: 83948-53-2(Hazardous Substances Data)

Usage

Chemical Properties

White low melting solid

Uses

3-(Boc-amino)propyl bromide can be used as an alkylating reagent for the synthesis of:Benzydamine analogs to be used as activators for soluble guanylate cyclase.N-substituted chromenotriazolopyrimidine, human murine double minute 2 (MDM2) inhibitor.Protected amines from piperidine derivatives to be further used for synthesis of sulfonamide series.It can also be used for the post-polymerization quaternization of polymers to synthesize functional cationic polymers and antimicrobial agents.

InChI:InChI=1/C8H16BrNO2/c1-8(2,3)12-7(11)10-6-4-5-9/h4-6H2,1-3H3,(H,10,11)

Upstream product

• 558-13-4 carbon tetrabromide 
• 58885-58-8 N-tert-butoxycarbonyl-3-aminopropanol 
• 216959-40-9 [(3-bromo-propyl)-tert-butoxycarbonyl-amino]-oxo-acetic acid ethyl ester 

Downstream Products

• 251369-17-2 1-(3-(4-(1-N-BOC-3-aminopropyl)piperidyl)propyl)-2-(4-chlorophenoxymethyl)-4-methylbenzimidazole 
• 256951-86-7 {3-[4-(4-fluoro-phenyl)-4-hydroxy-piperidin-1-yl]-propyl}-carbamic acid tert-butyl ester 
• 798567-32-5 (S)-t-butyl 3-(4-(3-t-butoxycarbonylaminopropoxy)-3-nitrophenyl)-2-(3-(trifluoromethyl)phenylsulfonamido)propionate 
• 943900-73-0 C₃₁H₄₁BrN₂O₉ 
• 892413-77-3 tert-butyl (3-(2-methoxy-5-nitrophenoxy)propyl)carbamate 
• 885594-72-9 tert-butyl N-[3-(3-bromophenoxy)propyl]carbamate 
• 1192364-65-0 tert-butyl 3-(2-iodophenoxy)propylcarbamate 
• 689294-33-5 tert-butyl 3-{N-formyl-N-[1-methyl-5-(tritylamino)-1H-pyrazol-4-yl] amino} propylcarbamate 
• 689295-08-7 tert-butyl (3-{N-formyl-N-[1-(2-hydroxyethyl)-5-(tritylamino)-1H-pyrazol-4-yl] amino} propyl) carbamate 
• 629646-55-5 3-[4-[3-(ethoxycarbonylmethoxy)phenyl]piperazin-1-yl]-N-t-butoxycarbonylpropylamine 
• 540779-40-6 ethyl (E)-4-[3'-(1-adamantyl)-4'-benzyloxyphenyl]-3-[(3'-tert-butoxycarboxamido)propoxy]cinnamate 
• 736992-51-1 ethyl (E)-3-[5-(adamant-1-yl)-2-(3-(tert-butoxycarbonylamino)propoxy)-4-hydroxy-2-methylbiphenyl-4-yl]acrylate 
• 754992-78-4 2-(3-(tert-butoxycarbonylamino)propoxy)benzoic acid 
• 496064-27-8 2-(3-(tert-butoxycarbonylamino)propoxy)benzoyl fluoride 

Relevant articles and documents

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Disclosed herein are phthalocyanine dyes, and conjugates thereof, useful as fluorescent reporters for bioassays, for optical imaging and as therapeutic conjugates as the photosensitizing agents in light-based therapies including photoimmuno therapy (PIT). Certain phthalocyanine dyes disclosed herein are water soluble, and possess photophysical and photochemical profiles useful for use in imaging or therapy.

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