2-Pentenoic acid, 3-methyl-5-oxo-5-phenyl-, ethyl ester

Base Information

• Chemical Name: 2-Pentenoic acid, 3-methyl-5-oxo-5-phenyl-, ethyl ester
• CAS No.: 82343-51-9
• Molecular Formula: C₁₄H₁₆O₃
• Molecular Weight: 232.279
• Mol file: 82343-51-9.mol

Synonyms:

Chemical Property of 2-Pentenoic acid, 3-methyl-5-oxo-5-phenyl-, ethyl ester

Chemical Property:

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Pentenoic acid, 3-methyl-5-oxo-5-phenyl-, ethyl ester

There total 4 articles about 2-Pentenoic acid, 3-methyl-5-oxo-5-phenyl-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 2-(trimethylsilyl)-3-methyl-3-butenoate (82343-39-3) + benzoyl chloride (98-88-4) → ethyl 3-methyl-5-oxo-5-phenyl-2-pentenoate (82343-51-9) + 4-methyl-6-phenyl-2H-pyran-2-one (4467-30-5)

Guidance literature:

With titanium tetrachloride; In dichloromethane; Yield given; 1.) -78 deg C, 15 min; 2.) room temp., 33 h;

DOI:10.1016/S0040-4039(00)86931-2

Reference yield:

ethyl 3-methyl-4-(tributylstannyl)-2-butenoate (92511-62-1) + benzoyl chloride (98-88-4) → ethyl 4-benzoyl-3-methyl-2-butenoate (117539-45-4) + ethyl 3-methyl-5-oxo-5-phenyl-2-pentenoate (82343-51-9)

Guidance literature:

trans benzyl(chloro)bis(triphenylphosphine)palladium(II); In chloroform; for 20h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Heating;

DOI:10.1039/c39880000086

Reference yield:

ethyl 3-methylbut-2-enoate (638-10-8) + benzoyl chloride (98-88-4) → ethyl 3-methyl-5-oxo-5-phenyl-2-pentenoate (82343-51-9)

Guidance literature:

With aluminum (III) chloride; for 5h; Reflux;

DOI:10.1021/ml400036z

upstream raw materials:

ethyl 3-methyl-4-(tributylstannyl)-2-butenoate

benzoyl chloride

ethyl 2-(trimethylsilyl)-3-methyl-3-butenoate

ethyl 3-methylbut-2-enoate

Downstream raw materials:

4-methyl-6-phenyl-2H-pyran-2-one

4-Methyl-6-phenyl-2H-pyran-2-thion

6-phenyl-4-methyl-1-hydroxypyridin-2(1H)-one