Benzoic acid, 4-[[(2S)-2-[[4-[[(2S)-2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-methyl-1- oxopentyl]amino]benzoyl]amino]-4-methyl-1-oxopentyl]amino]-, ethyl ester

Base Information

Chemical Name:Benzoic acid, 4-[[(2S)-2-[[4-[[(2S)-2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-methyl-1- oxopentyl]amino]benzoyl]amino]-4-methyl-1-oxopentyl]amino]-, ethyl ester
CAS No.:823786-70-5
Molecular Formula:C33H46N4O7
Molecular Weight:610.751
Hs Code.:

Benzoic acid,
4-[[(2S)-2-[[4-[[(2S)-2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-methyl-1-
oxopentyl]amino]benzoyl]amino]-4-methyl-1-oxopentyl]amino]-, ethyl
ester

Synonyms:

Suppliers and Price of Benzoic acid, 4-[[(2S)-2-[[4-[[(2S)-2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-methyl-1- oxopentyl]amino]benzoyl]amino]-4-methyl-1-oxopentyl]amino]-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Benzoic acid, 4-[[(2S)-2-[[4-[[(2S)-2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-methyl-1- oxopentyl]amino]benzoyl]amino]-4-methyl-1-oxopentyl]amino]-, ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Benzoic acid, 4-[[(2S)-2-[[4-[[(2S)-2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-methyl-1- oxopentyl]amino]benzoyl]amino]-4-methyl-1-oxopentyl]amino]-, ethyl ester

There total 1 articles about Benzoic acid, 4-[[(2S)-2-[[4-[[(2S)-2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-methyl-1- oxopentyl]amino]benzoyl]amino]-4-methyl-1-oxopentyl]amino]-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 94-09-7
p-aminoethylbenzoate

: (S)-2-[4-((S)-2-tert-Butoxycarbonylamino-4-methyl-pentanoylamino)-benzoylamino]-4-methyl-pentanoic acid

: 823786-70-5
4-{(S)-2-[4-((S)-2-tert-Butoxycarbonylamino-4-methyl-pentanoylamino)-benzoylamino]-4-methyl-pentanoylamino}-benzoic acid ethyl ester

Guidance literature:: With dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃;
DOI:10.1021/ja044310j

Reference yield:

: 823786-70-5
4-{(S)-2-[4-((S)-2-tert-Butoxycarbonylamino-4-methyl-pentanoylamino)-benzoylamino]-4-methyl-pentanoylamino}-benzoic acid ethyl ester

: C₃₀H₄₃N₅O₄

Guidance literature:: Multi-step reaction with 3 steps

1: 77 percent / aq. NaOH / ethanol / 20 °C

2: 73 percent / 1-hydroxybenzotriazole; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide / dimethylformamide / 20 °C

3: 2,2,2-trifluoroacetic acid / CH₂Cl₂ / 20 °C

With sodium hydroxide; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; trifluoroacetic acid; In ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ja044310j

Reference yield:

: 823786-70-5
4-{(S)-2-[4-((S)-2-tert-Butoxycarbonylamino-4-methyl-pentanoylamino)-benzoylamino]-4-methyl-pentanoylamino}-benzoic acid ethyl ester

: 823786-73-8
(1-{4-[1-(4-tert-butylcarbamoyl-phenylcarbamoyl)-3-methyl-butylcarbamoyl]-phenylcarbamoyl}-3-methyl-butyl)-carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / aq. NaOH / ethanol / 20 °C

2: 73 percent / 1-hydroxybenzotriazole; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide / dimethylformamide / 20 °C

With sodium hydroxide; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In ethanol; N,N-dimethyl-formamide;
DOI:10.1021/ja044310j