N-(2-Bromo-4-methylphenyl)-1-(quinoline-8-sulfonyl)piperidine-3-carboxamide

Base Information

Chemical Name:N-(2-Bromo-4-methylphenyl)-1-(quinoline-8-sulfonyl)piperidine-3-carboxamide
CAS No.:6774-49-8
Molecular Formula:C22H22BrN3O3S
Molecular Weight:216.347
Hs Code.:
ChEMBL ID:CHEMBL1899780
DSSTox Substance ID:DTXSID40410144

Synonyms:6774-49-8;N-(2-Bromo-4-methylphenyl)-1-(quinoline-8-sulfonyl)piperidine-3-carboxamide;N-(2-bromo-4-methylphenyl)-1-quinolin-8-ylsulfonylpiperidine-3-carboxamide;CHEMBL1899780;DTXSID40410144;HMS1916H06;HMS3536P15;AKOS002120347;AKOS021872831;NCGC00140734-01;K906-2073;N-(2-bromo-4-methylphenyl)-1-(quinolin-8-ylsulfonyl)piperidine-3-carboxamide

Suppliers and Price of N-(2-Bromo-4-methylphenyl)-1-(quinoline-8-sulfonyl)piperidine-3-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of N-(2-Bromo-4-methylphenyl)-1-(quinoline-8-sulfonyl)piperidine-3-carboxamide

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.511g/cm³
XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:487.05653
Heavy Atom Count:30
Complexity:713

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C=C1)NC(=O)C2CCCN(C2)S(=O)(=O)C3=CC=CC4=C3N=CC=C4)Br

Technology Process of N-(2-Bromo-4-methylphenyl)-1-(quinoline-8-sulfonyl)piperidine-3-carboxamide

There total 6 articles about N-(2-Bromo-4-methylphenyl)-1-(quinoline-8-sulfonyl)piperidine-3-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 1-(cyclohexylethynyl)-2-(methylsulfanyl)benzene

: 6774-49-8
2-(cyclohexyl)benzo[b]thiophene

Guidance literature:: With AuOH(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene); acetic acid; In toluene; at 100 ℃; for 20h;
DOI:10.1039/c8ob02196a

Reference yield: 84.0%

: 98437-23-1
benzo[b]thiophene-2-boronic acid

: 626-62-0
Cyclohexyl iodide

: 6774-49-8
2-(cyclohexyl)benzo[b]thiophene

Guidance literature:: With nickel(II) nitrate hexahydrate; potassium carbonate; 4,4'-di-tert-butyl-2,2'-bipyridine; In 1,4-dioxane; at 80 ℃; for 12h; Inert atmosphere; Sealed tube;
DOI:10.1002/adsc.201500346

Reference yield: 70.0%

: 108-85-0
1-bromocyclohexane

: 95-15-8,11095-43-5
Benzo[b]thiophene

: 6774-49-8
2-(cyclohexyl)benzo[b]thiophene

Guidance literature:: With iron(III) chloride; Cy₂NMgCl*LiCl; (1S,2S)-N,N'-dimethyl-1,2-diaminocyclohexane; In tetrahydrofuran; at 20 ℃; Inert atmosphere;
DOI:10.1021/ol101684u