2-(4-Methoxyphenyl)-1-(4-methylbenzene-1-sulfonyl)azetidine

Base Information

Chemical Name:2-(4-Methoxyphenyl)-1-(4-methylbenzene-1-sulfonyl)azetidine
CAS No.:824390-93-4
Molecular Formula:C17H19NO3S
Molecular Weight:317.409
Hs Code.:
DSSTox Substance ID:DTXSID10590821
Nikkaji Number:J2.134.792B

Synonyms:824390-93-4;2-(4-Methoxyphenyl)-1-tosylazetidine;2-(4-Methoxyphenyl)-1-(4-methylbenzene-1-sulfonyl)azetidine;2-(4-methoxyphenyl)-1-(4-methylphenyl)sulfonylazetidine;2-(4-methoxyphenyl)-1-(4-methylbenzenesulfonyl)azetidine;DTXSID10590821;AKOS030575768;SB51264;EN300-131218

Suppliers and Price of 2-(4-Methoxyphenyl)-1-(4-methylbenzene-1-sulfonyl)azetidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 2-(4-Methoxyphenyl)-1-(4-methylbenzene-1-sulfonyl)azetidine

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:317.10856464
Heavy Atom Count:22
Complexity:457

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)N2CCC2C3=CC=C(C=C3)OC

Technology Process of 2-(4-Methoxyphenyl)-1-(4-methylbenzene-1-sulfonyl)azetidine

There total 9 articles about 2-(4-Methoxyphenyl)-1-(4-methylbenzene-1-sulfonyl)azetidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 295344-96-6
C₁₇H₁₉NO₅S

: 824390-93-4
2-(4-methoxyphenyl)-1-(toluene-4-sulfonyl)-azetidine

Guidance literature:: With p-toluenesulfonyl chloride; potassium hydroxide; In tetrahydrofuran; at 20 ℃; Reflux;
DOI:10.1039/c5ob01140j

Reference yield: 71.0%

: 824390-90-1
4-methyl-N-(1-(4-methoxyphenyl)-allyl)-benzenesulfonamide

: 824390-93-4
2-(4-methoxyphenyl)-1-(toluene-4-sulfonyl)-azetidine

Guidance literature:: 4-methyl-N-(1-(4-methoxyphenyl)-allyl)-benzenesulfonamide; With dimethylsulfide borane complex; In tetrahydrofuran; at 20 ℃; for 12h;

With sodium hydroxide; ethanol; dihydrogen peroxide; In tetrahydrofuran; at 20 ℃; for 2h;

With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 0 - 20 ℃;
DOI:10.1021/ol048161l

Reference yield: 45.0%

: 908131-26-0
N-[3-hydroxy-1-(4-methoxy-phenyl)-propyl]-4-methyl-benzenesulfonamide

: 824390-93-4
2-(4-methoxyphenyl)-1-(toluene-4-sulfonyl)-azetidine

Guidance literature:: With p-toluenesulfonyl chloride; potassium hydroxide; In tetrahydrofuran; for 2h; Reflux; Inert atmosphere;
DOI:10.1021/acs.orglett.8b01394