N-(4-Methoxybenzylidene)-4-methylbenzenesulfonamide

Base Information

• Chemical Name: N-(4-Methoxybenzylidene)-4-methylbenzenesulfonamide
• CAS No.: 14674-38-5
• Molecular Formula: C15H15NO3S
• Molecular Weight: 289.355
• European Community (EC) Number: 624-804-1
• DSSTox Substance ID: DTXSID801322356
• ChEMBL ID: CHEMBL3213892
• Mol file: 14674-38-5.mol

Synonyms:N-(4-METHOXYBENZYLIDENE)-4-METHYLBENZENESULFONAMIDE;135822-88-7;(NE)-N-[(4-methoxyphenyl)methylidene]-4-methylbenzenesulfonamide;N-[(1E)-(4-methoxyphenyl)methylidene]-4-methylbenzene-1-sulfonamide;MLS000680121;(E)-N-(4-methoxybenzylidene)-4-methylbenzenesulfonamide;CHEMBL3213892;DTXSID801322356;AKOS002251431;SMR000324387;(E)-4-methyl-N-p-anisylidene-benzenesulfonamide;AB00079169-01;J-008257;F0016-0116;N-(4-Methoxybenzylidene)-4-methylbenzenesulfonamide, 97%;(E)-N-[(4-methoxyphenyl)methylidene]-4-methylbenzenesulfonamide

Chemical Property of N-(4-Methoxybenzylidene)-4-methylbenzenesulfonamide

Chemical Property:

• Melting Point: 127-132°C
• PSA: 64.11000
• LogP: 3.89220
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 289.07726451
• Heavy Atom Count: 20
• Complexity: 411

Purity/Quality:

97% ^*data from raw suppliers

N-(4-Methoxybenzylidene)-4-methylbenzenesulfonamide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): 2383265
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)N=CC2=CC=C(C=C2)OC
• Isomeric SMILES: CC1=CC=C(C=C1)S(=O)(=O)/N=C/C2=CC=C(C=C2)OC

Technology Process of N-(4-Methoxybenzylidene)-4-methylbenzenesulfonamide

There total 22 articles about N-(4-Methoxybenzylidene)-4-methylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N-[(4-methoxy-phenyl)-(toluene-4-sulfonyl)-methyl]-4-methyl-benzenesulfonamide → (E)-N-(4-methoxybenzylidene)-4-methylbenzenesulfonamide (14674-38-5,135822-88-7)

Guidance literature:

With sodium hydrogencarbonate; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1080/00397910601131387

Reference yield: 99.0%

4-methoxy-benzaldehyde (123-11-5) + toluene-4-sulfonamide (70-55-3) → (E)-N-(4-methoxybenzylidene)-4-methylbenzenesulfonamide (14674-38-5,135822-88-7)

Guidance literature:

With toluene-4-sulfonic acid; In toluene; Reflux;

DOI:10.1039/c1cc10678c

Reference yield: 97.0%

4-methoxy-benzaldehyde (123-11-5) + toluene-4-sulfonamide (70-55-3) → N-(4-methoxybenzylidene)-p-toluenesulfonamide (14674-38-5)

Guidance literature:

With pyrrolidine; In dichloromethane; at 60 ℃; for 24h; Concentration; Molecular sieve;

DOI:10.1021/ja4111418

upstream raw materials:

9-fluorenethione S-p-toluenesulfomimide

N-[1-(4-Methoxy-phenyl)-meth-(Z)-ylidene]-N'-[1-(4-methoxy-phenyl)-meth-(E)-ylidene]-hydrazine

4-toluenesulfonyl azide

4-methoxy-benzaldehyde