4-Nitroso-3-phenyl-5-(trifluoromethyl)-1H-pyrazole

Base Information

Chemical Name:4-Nitroso-3-phenyl-5-(trifluoromethyl)-1H-pyrazole
CAS No.:824969-35-9
Molecular Formula:C₁₀H₆F₃N₃O
Molecular Weight:241.172
Hs Code.:
ChEMBL ID:CHEMBL4776031
DSSTox Substance ID:DTXSID70571474
Nikkaji Number:J897.669D
Wikidata:Q82459562

Synonyms:4-Nitroso-3-phenyl-5-(trifluoromethyl)-1H-pyrazole;3-TRIFLUOROMETHYL-5-PHENYL-4H-PYRAZOL-4-ONE OXIME;4-nitroso-5-phenyl-3-trifluoromethyl-1H-pyrazole;824969-35-9;SCHEMBL4712032;CHEMBL4776031;SCHEMBL15715941;DTXSID70571474;MFCD07779678;AKOS025211837;4-hydroxyimino-5-phenyl-3-tri-fluoromethylpyrazole

Suppliers and Price of 4-Nitroso-3-phenyl-5-(trifluoromethyl)-1H-pyrazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-Nitroso-3-phenyl-5-(trifluoromethyl)-1H-pyrazole

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:241.04629631
Heavy Atom Count:17
Complexity:279

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NNC(=C2N=O)C(F)(F)F

Technology Process of 4-Nitroso-3-phenyl-5-(trifluoromethyl)-1H-pyrazole

There total 5 articles about 4-Nitroso-3-phenyl-5-(trifluoromethyl)-1H-pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 1291099-85-8
3-hydroxy-4-nitroso-5-phenyl-3-trifluoromethyl-2,3-dihydro-1H-pyrazole

: 824969-35-9,1291099-88-1
4-nitroso-5-phenyl-3-(trifluoromethyl)-1H-pyrazole

Guidance literature:: at 90 ℃; for 3h;
DOI:10.1007/s11172-010-0341-7

Reference yield:

: 4,4,4-trifluoro-2-(hydroxyimino)-1-phenylbutane-1,3-dione

: 824969-35-9,1291099-88-1
4-nitroso-5-phenyl-3-(trifluoromethyl)-1H-pyrazole

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine hydrate / water / 10 °C

2: 3 h / 90 °C

With hydrazine hydrate; In water;
DOI:10.1007/s11172-010-0341-7

Reference yield:

: 41463-86-9
4,4,4-trifluoro-3-hydroxy-1-phenylbut-2-en-1-one

: 824969-35-9,1291099-88-1
4-nitroso-5-phenyl-3-(trifluoromethyl)-1H-pyrazole

Guidance literature:: Multi-step reaction with 3 steps

1: sodium nitrite; acetic acid / 10 °C

2: hydrazine hydrate / water / 10 - 20 °C

3: 3 h / 90 °C

With hydrazine hydrate; acetic acid; sodium nitrite; In water;
DOI:10.1016/j.ejmech.2020.112768