1,2-Bis(phenylsulfonyl)ethane

Base Information

• Chemical Name: 1,2-Bis(phenylsulfonyl)ethane
• CAS No.: 599-94-0
• Molecular Formula: C14H14 O4 S2
• Molecular Weight: 310.395
• Hs Code.: 2904100000
• European Community (EC) Number: 209-979-0
• NSC Number: 2716
• DSSTox Substance ID: DTXSID30208613
• Nikkaji Number: J137.010C
• Wikidata: Q83082705
• ChEMBL ID: CHEMBL1888648
• Mol file: 599-94-0.mol

Synonyms:1,2-bis(phenylsulfonyl)ethane

Chemical Property of 1,2-Bis(phenylsulfonyl)ethane

Chemical Property:

• Vapor Pressure: 3.02E-12mmHg at 25°C
• Melting Point: 179-180°C
• Boiling Point: 566°Cat760mmHg
• Flash Point: 380.4°C
• PSA: 85.04000
• Density: 1.327g/cm³
• LogP: 4.09580
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 310.03335127
• Heavy Atom Count: 20
• Complexity: 436

Purity/Quality:

99% ^*data from raw suppliers

1,2-BIS(PHENYLSULFONYL)ETHANE 95.00% ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)S(=O)(=O)CCS(=O)(=O)C2=CC=CC=C2

Technology Process of 1,2-Bis(phenylsulfonyl)ethane

There total 50 articles about 1,2-Bis(phenylsulfonyl)ethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

1,2-bis(phenylthio)ethane (622-20-8) → 1,2-bis(phenylsulfonyl)ethane (599-94-0)

Guidance literature:

With (PF6)2; periodic acid; In pyridine; Ambient temperature;

DOI:10.1016/S0040-4039(98)01518-4

Reference yield: 80.0%

C14H13BrO4S2 → 1,2-bis(phenylsulfonyl)ethane (599-94-0) + PVS (5535-48-8)

Guidance literature:

With methanol; triphenylphosphine; at 25 ℃;

DOI:10.1039/c39930001609

Reference yield: 75.0%

PVS (5535-48-8) + piloty's acid (599-71-3) → 1,2-bis(phenylsulfonyl)ethane (599-94-0)

Guidance literature:

With sodium acetate; In methanol; at 60 ℃; for 18h;

DOI:10.3390/molecules22010039

upstream raw materials:

benzenesulphinyl chloride

2-chloroethyl phenyl sulfone

sodium benzenesulfonate

ethanol

Downstream raw materials:

benzenesulfonyl chloride

ethanol

Benzenesulfinic acid

2-(phenylsulfonyl)ethanol

Refernces

• 1、 Bin, Yunhui,Hua, Ruimao. "Synthesis of alkyl aryl sulfones via reaction of N-arylsulfonyl hydroxyamines with electron-deficient alkenes". . . Retrieved 2017/01/24.
• 2、 Bhunia, Anup,Yetra, Santhivardhana Reddy,Bhojgude, Sachin Suresh,Biju, Akkattu T.. "Efficient synthesis of γ-keto sulfones by NHC-catalyzed intermolecular Stetter reaction". supporting information; experimental part. p. 2830 - 2833. Retrieved 2012/07/17.