1H-Purin-6-amine, 8-[(3,4,5-trimethoxyphenyl)thio]-

Base Information

Chemical Name:1H-Purin-6-amine, 8-[(3,4,5-trimethoxyphenyl)thio]-
CAS No.:827302-37-4
Molecular Formula:C14H15N5O3S
Molecular Weight:333.371
Hs Code.:
DSSTox Substance ID:DTXSID90457408
Nikkaji Number:J2.118.872G
Wikidata:Q82280248

Synonyms:1H-Purin-6-amine, 8-[(3,4,5-trimethoxyphenyl)thio]-;827302-37-4;SCHEMBL3121816;DTXSID90457408;LMYMRNJBAALZRX-UHFFFAOYSA-N;8-(3,4,5-Trimethoxyphenylthio)-9H-purine-6-amine;8-(3,4,5-trimethoxy-phenylsulfanyl)-9H-purin-6-ylamine

Suppliers and Price of 1H-Purin-6-amine, 8-[(3,4,5-trimethoxyphenyl)thio]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1H-Purin-6-amine, 8-[(3,4,5-trimethoxyphenyl)thio]-

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:5
Exact Mass:333.08956053
Heavy Atom Count:23
Complexity:379

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=CC(=C1OC)OC)SC2=NC3=NC=NC(=C3N2)N

Technology Process of 1H-Purin-6-amine, 8-[(3,4,5-trimethoxyphenyl)thio]-

There total 4 articles about 1H-Purin-6-amine, 8-[(3,4,5-trimethoxyphenyl)thio]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 16807-30-0
3,4,5-trimethoxyphenylmercaptan

: 6974-78-3
8-bromoadenine

: 827302-37-4
8-(3,4,5-trimethoxy-phenylsulfanyl)adenine

Guidance literature:: 3,4,5-trimethoxyphenylmercaptan; With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

8-bromoadenine; In N,N-dimethyl-formamide; at 90 ℃; for 14h;
DOI:10.1021/jm049012b

Reference yield:

: 66224-66-6,66224-67-7,66224-68-8,66224-69-9,134434-48-3,134434-49-4,134454-76-5,134461-75-9
adenine

: 827302-37-4
8-(3,4,5-trimethoxy-phenylsulfanyl)adenine

Guidance literature:: Multi-step reaction with 2 steps

1.1: bromine / H₂O / 20 °C

2.1: K₂CO₃ / dimethylformamide / 1 h / 20 °C

2.2: dimethylformamide / 14 h / 90 °C

With bromine; potassium carbonate; In water; N,N-dimethyl-formamide;
DOI:10.1021/jm049012b

Reference yield:

: 24313-88-0
3,4,5-Trimethoxyaniline

: 827302-37-4
8-(3,4,5-trimethoxy-phenylsulfanyl)adenine

Guidance literature:: Multi-step reaction with 3 steps

1.1: aq. HCl; NaNO₂ / 0 °C

1.2: 58 percent / H₂O / 0.67 h / 50 °C

2.1: 1.18 g / LiAlH₄ / tetrahydrofuran / 1 h / Heating

3.1: K₂CO₃ / dimethylformamide / 1 h / 20 °C

3.2: dimethylformamide / 14 h / 90 °C

With hydrogenchloride; lithium aluminium tetrahydride; potassium carbonate; sodium nitrite; In tetrahydrofuran; N,N-dimethyl-formamide; 1.1: Leuckart reaction;
DOI:10.1021/jm049012b