3-(cyclohexylmethyl)-1-(4-aminophenyl)-3-azabicyclo(3.1.0)hexane-2,4-dione

Base Information

Chemical Name:3-(cyclohexylmethyl)-1-(4-aminophenyl)-3-azabicyclo(3.1.0)hexane-2,4-dione
CAS No.:133986-32-0
Molecular Formula:C18H22 N2 O2
Molecular Weight:298.385
Hs Code.:
Mol file:133986-32-0.mol

Synonyms:3-Azabicyclo[3.1.0]hexane-2,4-dione,1-(4-aminophenyl)-3-(cyclohexylmethyl)-, (?à)-

Suppliers and Price of 3-(cyclohexylmethyl)-1-(4-aminophenyl)-3-azabicyclo(3.1.0)hexane-2,4-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of 3-(cyclohexylmethyl)-1-(4-aminophenyl)-3-azabicyclo(3.1.0)hexane-2,4-dione

Chemical Property:

Vapor Pressure:2.35E-10mmHg at 25°C
Boiling Point:505.8°C at 760 mmHg
Flash Point:259.7°C
PSA：63.40000
Density:1.281g/cm³
LogP:2.99470

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-(cyclohexylmethyl)-1-(4-aminophenyl)-3-azabicyclo(3.1.0)hexane-2,4-dione

There total 4 articles about 3-(cyclohexylmethyl)-1-(4-aminophenyl)-3-azabicyclo(3.1.0)hexane-2,4-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 93579-32-9
3-cyclohexylmethyl-1-(4-nitrophenyl)-3-azabicyclo[3.1.0]hexane-2,4-dione

: 133986-32-0
1-(4-aminophenyl)-3-cyclohexylmethyl-3-azabicyclo[3.1.0]hexane-2,4-dione

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethyl acetate;
DOI:10.1021/jm00108a013

Reference yield:

: 63162-65-2
1-phenylcyclopropanedicarboxylic acid

: 133986-32-0
1-(4-aminophenyl)-3-cyclohexylmethyl-3-azabicyclo[3.1.0]hexane-2,4-dione

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) xylene, reflux, 5 h, 2.) xylene, reflux, 15 h

2: 60 percent / concd. sulfuric acid, nitric acid / 2 h / 10 °C

3: 84 percent / H₂ / 5percent Pd/C / ethyl acetate

With sulfuric acid; hydrogen; nitric acid; palladium on activated charcoal; In ethyl acetate;
DOI:10.1021/jm00108a013

Reference yield:

: 133986-33-1
3-Cyclohexylmethyl-1-phenyl-3-aza-bicyclo[3.1.0]hexane-2,4-dione

: 133986-32-0
1-(4-aminophenyl)-3-cyclohexylmethyl-3-azabicyclo[3.1.0]hexane-2,4-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 60 percent / concd. sulfuric acid, nitric acid / 2 h / 10 °C

2: 84 percent / H₂ / 5percent Pd/C / ethyl acetate

With sulfuric acid; hydrogen; nitric acid; palladium on activated charcoal; In ethyl acetate;
DOI:10.1021/jm00108a013