1-Phenylcyclopropane-1,2-dicarboxylic acid

Base Information

Chemical Name:1-Phenylcyclopropane-1,2-dicarboxylic acid
CAS No.:63162-65-2
Molecular Formula:C11H10O4
Molecular Weight:206.19500
Hs Code.:
DSSTox Substance ID:DTXSID90507957

Synonyms:1-phenylcyclopropane-1,2-dicarboxylic acid;63162-65-2;SCHEMBL11077137;DTXSID90507957;CPBWKVACBJABJR-UHFFFAOYSA-N;EN300-295586;F52560

Suppliers and Price of 1-Phenylcyclopropane-1,2-dicarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 1-Phenylcyclopropane-1,2-dicarboxylic acid

Chemical Property:

PSA：74.60000
LogP:1.11350
XLogP3:0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:206.05790880
Heavy Atom Count:15
Complexity:293

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(C1(C2=CC=CC=C2)C(=O)O)C(=O)O

Technology Process of 1-Phenylcyclopropane-1,2-dicarboxylic acid

There total 5 articles about 1-Phenylcyclopropane-1,2-dicarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 731-05-5,731-06-6,731-07-7,77053-64-6
cis (±)-diethyl 1-phenylcyclopropane-1,2-dicarboxylate

: 882-72-4,882-73-5,55167-52-7,55167-53-8,55221-22-2,55221-23-3,63162-65-2,134052-45-2
cis (±)-1-phenylcyclopropane-1,2-dicarboxylic acid

Guidance literature:: With potassium hydroxide; In ethanol; water; for 6h; Heating;
DOI:10.1021/jm00137a002

Reference yield:

: 101-97-3
Ethyl 2-phenylethanoate

: 882-72-4,882-73-5,55167-52-7,55167-53-8,55221-22-2,55221-23-3,63162-65-2,134052-45-2
cis (±)-1-phenylcyclopropane-1,2-dicarboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 85 percent / NBS, 48percent aq. HBr / CCl₄ / Heating

2: 53 percent / NaOEt / diethyl ether / 24 h / Ambient temperature

3: 80 percent / KOH / ethanol; H₂O / 6 h / Heating

With potassium hydroxide; N-Bromosuccinimide; hydrogen bromide; sodium ethanolate; In tetrachloromethane; diethyl ether; ethanol; water;
DOI:10.1021/jm00137a002

Reference yield:

: 2882-19-1,2216-90-2
ethyl 2-phenyl-2-bromoacetate

: 882-72-4,882-73-5,55167-52-7,55167-53-8,55221-22-2,55221-23-3,63162-65-2,134052-45-2
cis (±)-1-phenylcyclopropane-1,2-dicarboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 53 percent / NaOEt / diethyl ether / 24 h / Ambient temperature

2: 80 percent / KOH / ethanol; H₂O / 6 h / Heating

With potassium hydroxide; sodium ethanolate; In diethyl ether; ethanol; water;
DOI:10.1021/jm00137a002