2-Methyl-3-(4-nitrophenyl)quinazolin-4-one

Base Information

Chemical Name:2-Methyl-3-(4-nitrophenyl)quinazolin-4-one
CAS No.:1788-96-1
Molecular Formula:C15H11N3O3
Molecular Weight:281.271
Hs Code.:
NSC Number:400974
DSSTox Substance ID:DTXSID90275684
Wikidata:Q82005822
ChEMBL ID:CHEMBL580891
Mol file:1788-96-1.mol

Synonyms:GNF-Pf-1297;1788-96-1;NSC 400974;NSC400974;CBMicro_009015;Oprea1_317260;Oprea1_492061;2-Methyl-3-(4-nitro-phenyl)-3H-quinazolin-4-one;MLS001202713;CHEMBL580891;DTXSID90275684;HMS2814L19;SMSF0003585;AKOS000540935;CB11720;NSC-400974;NCGC00244994-01;SMR000504746;BIM-0008964.P001

Suppliers and Price of 2-Methyl-3-(4-nitrophenyl)quinazolin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 2-Methyl-3-(4-nitrophenyl)quinazolin-4-one

Chemical Property:

Vapor Pressure:6.59E-10mmHg at 25°C
Boiling Point:494.2°Cat760mmHg
Flash Point:252.7°C
Density:1.36g/cm³
XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:281.08004122
Heavy Atom Count:21
Complexity:463

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC2=CC=CC=C2C(=O)N1C3=CC=C(C=C3)[N+](=O)[O-]

Technology Process of 2-Methyl-3-(4-nitrophenyl)quinazolin-4-one

There total 9 articles about 2-Methyl-3-(4-nitrophenyl)quinazolin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4
anthranilic acid

: 100-01-6,104810-17-5
4-nitro-aniline

: 75-36-5
acetyl chloride

: 1788-96-1
2-methyl-3-(4-nitrophenyl)-4-oxo-3,4-dihydroquinazoline

Guidance literature:: for 0.0833333h; microwave irradiation;
DOI:10.1080/00304940509354972

Reference yield: 89.0%

: 100-01-6,104810-17-5
4-nitro-aniline

: 89-52-1
o-acetylamino-benzoic acid

: 1788-96-1
2-methyl-3-(4-nitrophenyl)-4-oxo-3,4-dihydroquinazoline

Guidance literature:: With phosphorus trichloride; In acetonitrile; at 50 ℃; for 20h;
DOI:10.1021/jo049118e

Reference yield: 80.0%

: 108-24-7
acetic anhydride

: 118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4
anthranilic acid

: 100-01-6,104810-17-5
4-nitro-aniline

: 1788-96-1
2-methyl-3-(4-nitrophenyl)-4-oxo-3,4-dihydroquinazoline

Guidance literature:: With superparamagnetic N-(silyloxypropyl)guanidine functionalized γ-Fe₂O₃ based sulfonic acid; In neat (no solvent); at 70 ℃; Microwave irradiation; Green chemistry;
DOI:10.1039/d1ra05560g