Cyclooctanol

Base Information

• Chemical Name: Cyclooctanol
• CAS No.: 696-71-9
• Molecular Formula: C8H16O
• Molecular Weight: 128.214
• Hs Code.: 2906 19 00
• European Community (EC) Number: 211-800-6
• NSC Number: 60162
• UNII: N948SW87NY
• DSSTox Substance ID: DTXSID80219875
• Nikkaji Number: J31.679B
• Wikidata: Q2577904
• ChEMBL ID: CHEMBL457729
• Mol file: 696-71-9.mol

Synonyms:cyclooctanol

Chemical Property of Cyclooctanol

Chemical Property:

• Vapor Pressure: 0.068mmHg at 25°C
• Melting Point: 14 - 15 °C
• Refractive Index: n20/D 1.486(lit.)
• Boiling Point: 203.228 °C at 760 mmHg
• PKA: 15.31±0.20(Predicted)
• Flash Point: 86.111 °C
• Density: 0.923 g/cm³
• Storage Temp.: Store below +30°C.
• Solubility.: Miscible with acetone.
• Water Solubility.: 6.576g/L(temperature not stated)
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 128.120115130
• Heavy Atom Count: 9
• Complexity: 63

Purity/Quality:

98% ^*data from raw suppliers

Cyclooctanol >98.0%(GC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,Xi
• Hazard Codes: Xn,Xi
• Statements: 36/38-22
• Safety Statements: 37/39-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1CCCC(CCC1)O
• Uses: Cyclooctanol is a key starting material used for the preparation of cylooctanone by using a chromic acid reagent.

Technology Process of Cyclooctanol

There total 118 articles about Cyclooctanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

cycloactanone (502-49-8) → cyclooctanol (696-71-9)

Guidance literature:

With aluminum oxide; sodium tetrahydroborate; In hexane; at 30 ℃; for 3h;

DOI:10.1039/a709081a

Reference yield: 99.0%

2-Cyclooctyloxy-tetrahydro-pyran (88773-85-7) → cyclooctanol (696-71-9)

Guidance literature:

Nafion-H; In methanol; for 2h;

DOI:10.1055/s-1983-30553

Reference yield: 99.0%

(Z)-cyclooct-4-enol (4277-34-3) → cyclooctanol (696-71-9)

Guidance literature:

(Z)-cyclooct-4-enol; With pyridinium p-toluenesulfonate; In 1,2-dichloro-ethane; at 80 ℃; for 20h;

With triethylamine; In dichloromethane; at 20 ℃; for 6h;

With trifluoroacetic acid; In methanol; dichloromethane; at 140 ℃; for 0.0666667h; Further stages.; microwave irradiation;

DOI:10.1021/jo0622173

upstream raw materials:

cycloactanone

Cyclooctene oxide

1,5-cis,cis-cyclooctadiene

cis-Cyclooctene

Downstream raw materials:

Cyclooctyl 2,4-Dinitrobenzolsulfenat

cyclooctyl acetate

Chlorameisensaeure-cyclooctylester

Propionic acid cyclooctyl ester