4-Chloromethyl-7-benzyloxy-2H-chromen-2-one

Base Information

Chemical Name:4-Chloromethyl-7-benzyloxy-2H-chromen-2-one
CAS No.:828265-69-6
Molecular Formula:C17H13ClO3
Molecular Weight:300.741
Hs Code.:
DSSTox Substance ID:DTXSID70464170
Wikidata:Q82289386

Synonyms:4-Chloromethyl-7-benzyloxy-2H-chromen-2-one;828265-69-6;SCHEMBL4203723;DTXSID70464170;DPKFXKRLUDIOHP-UHFFFAOYSA-N

Suppliers and Price of 4-Chloromethyl-7-benzyloxy-2H-chromen-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-Chloromethyl-7-benzyloxy-2H-chromen-2-one

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:300.0553220
Heavy Atom Count:21
Complexity:401

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC2=CC3=C(C=C2)C(=CC(=O)O3)CCl

Technology Process of 4-Chloromethyl-7-benzyloxy-2H-chromen-2-one

There total 2 articles about 4-Chloromethyl-7-benzyloxy-2H-chromen-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 25392-41-0
4-chloromethyl-7-hydroxycoumarin

: 100-39-0
benzyl bromide

: 828265-69-6
7-(benzyloxy)-4-(chloromethyl)-2H-chromen-2-one

Guidance literature:: With potassium carbonate; In ethanol; for 2h; Reflux;
DOI:10.1021/jm9010127

Reference yield:

: 108-46-3
recorcinol

: 828265-69-6
7-(benzyloxy)-4-(chloromethyl)-2H-chromen-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 25 percent / H₂SO₄ / 6 h / 120 °C

2: 50 percent / K₂CO₃ / ethanol / 3 h / Heating

With sulfuric acid; potassium carbonate; In ethanol;
DOI:10.1021/jm049535j