2-Bromo-5-(dimethylamino)benzaldehyde

Base Information

Chemical Name:2-Bromo-5-(dimethylamino)benzaldehyde
CAS No.:828916-47-8
Molecular Formula:C9H10BrNO
Molecular Weight:228.088
Hs Code.:
DSSTox Substance ID:DTXSID00693890
Nikkaji Number:J3.204.944C
Wikidata:Q82622868

Synonyms:2-Bromo-5-(dimethylamino)benzaldehyde;828916-47-8;DTXSID00693890;AKOS015904262

Suppliers and Price of 2-Bromo-5-(dimethylamino)benzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-Bromo-5-(dimethylamino)benzaldehyde

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:226.99458
Heavy Atom Count:12
Complexity:161

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)C1=CC(=C(C=C1)Br)C=O

Technology Process of 2-Bromo-5-(dimethylamino)benzaldehyde

There total 3 articles about 2-Bromo-5-(dimethylamino)benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 163913-92-6
5-(N,N-dimethylamino)-2-bromobenzyl alcohol

: 828916-47-8
5-(N,N-dimethylamino)-2-bromobenzaldehyde

Guidance literature:: 5-(N,N-dimethylamino)-2-bromobenzyl alcohol; With oxalyl dichloride; dimethyl sulfoxide; In dichloromethane; at -70 ℃; for 0.25h; Inert atmosphere; Schlenk technique;

With triethylamine; In dichloromethane; at -60 - 20 ℃; for 0.75h; Inert atmosphere;
DOI:10.1002/chem.201202817

Reference yield: 90.0%

: 619-22-7
3-(dimethylamino)benzaldehyde

: 828916-47-8
5-(N,N-dimethylamino)-2-bromobenzaldehyde

Guidance literature:: With N-Bromosuccinimide; In dichloromethane; at 0 - 20 ℃; for 3h;
DOI:10.1021/acs.joc.7b01260

Reference yield:

: 99-64-9
3-(dimethylamino)benzoic acid

: 828916-47-8
5-(N,N-dimethylamino)-2-bromobenzaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / lithium aluminum hydride / tetrahydrofuran / 1 h / 20 °C

2: 85 percent / manganese dioxide / CH₂Cl₂ / 4 h / 20 °C

3: 87 percent / 1,3-dibromo-5,5-dimethylhydantoin / CH₂Cl₂ / Heating

With manganese(IV) oxide; lithium aluminium tetrahydride; 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.tet.2004.08.056