2-Cyclopentene-1-acetamide, N-(2,6-dibromo-4-fluorophenyl)-, (1R)-

Base Information

Chemical Name:2-Cyclopentene-1-acetamide, N-(2,6-dibromo-4-fluorophenyl)-, (1R)-
CAS No.:828932-39-4
Molecular Formula:C13H12Br2FNO
Molecular Weight:377.051
Hs Code.:
DSSTox Substance ID:DTXSID80463578
Nikkaji Number:J2.140.282F
Wikidata:Q82288523

Synonyms:828932-39-4;2-Cyclopentene-1-acetamide, N-(2,6-dibromo-4-fluorophenyl)-, (1R)-;DTXSID80463578;AKOS015962714

Suppliers and Price of 2-Cyclopentene-1-acetamide, N-(2,6-dibromo-4-fluorophenyl)-, (1R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2-Cyclopentene-1-acetamide, N-(2,6-dibromo-4-fluorophenyl)-, (1R)-

Chemical Property:

XLogP3:4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:376.92492
Heavy Atom Count:18
Complexity:325

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(C=C1)CC(=O)NC2=C(C=C(C=C2Br)F)Br
Isomeric SMILES:C1C[C@@H](C=C1)CC(=O)NC2=C(C=C(C=C2Br)F)Br

Technology Process of 2-Cyclopentene-1-acetamide, N-(2,6-dibromo-4-fluorophenyl)-, (1R)-

There total 4 articles about 2-Cyclopentene-1-acetamide, N-(2,6-dibromo-4-fluorophenyl)-, (1R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 344-18-3
2,6-dibromo-4-fluoroaniline

: (R)-Cyclopent-2-enyl-acetyl chloride

: 828932-39-4
2-[(1R)-cyclopent-2-en-1-yl]-N-(2,6-dibromo-4-fluorophenyl)acetamide

Guidance literature:: In N,N-dimethyl acetamide; at 4 ℃; for 4h;
DOI:10.1021/jo048305+

Reference yield:

: 696-67-3
(-)-(R)-cyclopent-2-en-1-yl-acetic acid

: 828932-39-4
2-[(1R)-cyclopent-2-en-1-yl]-N-(2,6-dibromo-4-fluorophenyl)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl chloride / DMF / CH₂Cl₂ / 4 - 20 °C

2: 76 percent / N,N-dimethyl-acetamide / 4 h / 4 °C

With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; N,N-dimethyl acetamide;
DOI:10.1021/jo048305+

Reference yield:

: 828932-38-3
(S)-2-Cyclopent-2-enyl-malonic acid

: 828932-39-4
2-[(1R)-cyclopent-2-en-1-yl]-N-(2,6-dibromo-4-fluorophenyl)acetamide

Guidance literature:: Multi-step reaction with 3 steps

1: HOAc / 48 h / 120 °C

2: oxalyl chloride / DMF / CH₂Cl₂ / 4 - 20 °C

3: 76 percent / N,N-dimethyl-acetamide / 4 h / 4 °C

With oxalyl dichloride; acetic acid; N,N-dimethyl-formamide; In dichloromethane; N,N-dimethyl acetamide;
DOI:10.1021/jo048305+