696-67-3Relevant academic research and scientific papers
A simple preparation of (R)-(2-cyclopentenyl)acetic acid and (R)-(2-cyclohexenyl)acetic acid using β-diastereoselective radical cyclization in the presence of Lewis acid
Nishida,Hayashi,Yamaura,Yanaginuma,Yonemitsu,Nishida,Kawahara
, p. 269 - 272 (2007/10/02)
The alkenyl radical generated from (-)-8-phenylmenthyl 7-iodo-2,6-heptadienoate smoothly cyclized to afford (R)-(2-cyclopentenyl)acetate with 88% de in 90% yield. (R)-(2-Cyclohexenyl)acetate was also obtained with 84% de in 72% yield under the same conditions. The presence of Lewis acid is essential for high diastereoselectivity and chemical yield.
Asymmetric Catalysis by Vitamin B12: The Isomerization of Achiral Cyclopropanes to Optically Active Olefins
Troxler, Thomas,Scheffold, Rolf
, p. 1193 - 1202 (2007/10/02)
Achiral spiroactivated cyclopropanes are isomerized to optically active (R)-(cycloalk-2-enyl)-Meldrum's acids (= (R)-5-(cycloalk-2-enyl)-2,2-dimethyl-1,3-dioxane-4,6-diones) in high yield and ee's up to 86percent by catalytic amounts of cob(I)alamin in po
