2-Pyrrolidinone, 1-[(2-bromophenyl)sulfonyl]-

Base Information

Chemical Name:2-Pyrrolidinone, 1-[(2-bromophenyl)sulfonyl]-
CAS No.:830319-67-0
Molecular Formula:C10H10BrNO3S
Molecular Weight:304.164
Hs Code.:
DSSTox Substance ID:DTXSID10479884
Wikidata:Q82314210

Synonyms:830319-67-0;2-Pyrrolidinone, 1-[(2-bromophenyl)sulfonyl]-;DTXSID10479884;AKOS010466542

Suppliers and Price of 2-Pyrrolidinone, 1-[(2-bromophenyl)sulfonyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-Pyrrolidinone, 1-[(2-bromophenyl)sulfonyl]-

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:302.95648
Heavy Atom Count:16
Complexity:376

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC(=O)N(C1)S(=O)(=O)C2=CC=CC=C2Br

Technology Process of 2-Pyrrolidinone, 1-[(2-bromophenyl)sulfonyl]-

There total 1 articles about 2-Pyrrolidinone, 1-[(2-bromophenyl)sulfonyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 616-45-5
2-pyrrolidinon

: 2905-25-1
o-bromobenzenesulfonyl chloride

: 830319-67-0
1-(2-bromobenzenesulfonyl)pyrrolidin-2-one

Guidance literature:: With n-butyllithium; In tetrahydrofuran; hexane; at 0 ℃; for 1h;
DOI:10.1021/ol0480123

Reference yield: 83.0%

: 830319-67-0
1-(2-bromobenzenesulfonyl)pyrrolidin-2-one

: 830319-68-1
1-(2-bromobenzenesulfonyl)pyrrolidin-2-ol

Guidance literature:: With diisobutylaluminium hydride; In hexane; dichloromethane; at -78 - -40 ℃; for 1h;
DOI:10.1021/ol0480123

Reference yield:

: 830319-67-0
1-(2-bromobenzenesulfonyl)pyrrolidin-2-one

: 13214-66-9
4-phenyl-1-butylamine

Guidance literature:: Multi-step reaction with 5 steps

1.1: 83 percent / i-Bu₂AlH / CH₂Cl₂; hexane / 1 h / -78 - -40 °C

2.1: 83 percent / citric acid monohydrate / toluene / 6 h / Heating

3.1: 67 percent / Pd(OAc)2; triphenylphosphine; K₂CO₃ / dimethylformamide / 16 h / 110 °C

4.1: 87 percent / H₂ / Pd/C / ethanol / 15 h / 20 °C

5.1: lithium; NH₃ / tetrahydrofuran / 3 h / -78 °C

5.2: 88 percent / NH₄Cl

With palladium diacetate; ammonia; hydrogen; lithium; diisobutylaluminium hydride; potassium carbonate; triphenylphosphine; citric acid; palladium on activated charcoal; In tetrahydrofuran; ethanol; hexane; dichloromethane; N,N-dimethyl-formamide; toluene; 3.1: Heck reaction;
DOI:10.1021/ol0480123