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Product FOB Price Min.Order Supply Ability Supplier
2-Pyrrolidinone CAS 616-45-5 High Purity
Cas No: 616-45-5
USD $ 1.0-2.0 / Kilogram 1 Kilogram 5000 Kilogram/Month HUBEI AOKS BIO-TECH CO.,LTD Contact Supplier

616-45-5 Usage




2-pyrrolidone carboxylic acid, also known as pyroglutamic acid, is a derivative of the glutamine and glutamate. It is contained in many kinds of proteins including bacteriorhodopsin. It is a nonessential nutrient which can be normally generated during the glutathione cycle process inside the human body. It is also contained in fruits and vegetables. Pyroglutamic acid has many physiological functions and healthy effects. Its L-form can increase the activity off neurotransmitter acetylcholine and can be used in the production of the neurotransmitters gramma-aminobutyric acid (GABA) as well as glycine. Based on this, L-pyroglutamic acid is beneficial to brain function, being capable of supporting memory and learning as well as alleviating anxiety. In addition, its sodium-form product (sodium pyroglutamate), as a humectant, can be used for dry skin and hair products.


2-Pyrrolidinone is a widely used organic polar solvent for various applications. 2-Pyrrolidinone is also an intermediate in the manufacture of polymers.

Chemical Properties

Clear colorless liquid or low melting solid


ChEBI: The simplest member of the class of pyrrolidin-2-ones, consisting of pyrrolidine in which the hydrogens at position 2 are replaced by an oxo group. The lactam arising by the formal intramolecular condensation of the amino and carboxy groups of gamm -aminobutyric acid (GABA).

616-45-5 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
Sigma-Aldrich (83300)  2-Pyrrolidinone  purum, ≥98.0% (GC) 616-45-5 83300-1L 718.38CNY Detail
Sigma-Aldrich (83300)  2-Pyrrolidinone  purum, ≥98.0% (GC) 616-45-5 83300-250ML 274.95CNY Detail
Aldrich (P74370)  2-Pyrrolidinone  99% 616-45-5 P74370-20KG 9,330.75CNY Detail
Aldrich (P74370)  2-Pyrrolidinone  99% 616-45-5 P74370-1KG 620.10CNY Detail
Aldrich (P74370)  2-Pyrrolidinone  99% 616-45-5 P74370-500G 362.70CNY Detail
Aldrich (P74370)  2-Pyrrolidinone  99% 616-45-5 P74370-25G 297.18CNY Detail
Aldrich (240338)  2-Pyrrolidinone  ≥99% 616-45-5 240338-50G 689.13CNY Detail
Sigma-Aldrich (Y0000659)  Pyrrolidone  European Pharmacopoeia (EP) Reference Standard 616-45-5 Y0000659 1,880.19CNY Detail



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017


1.1 GHS Product identifier

Product name pyrrolidin-2-one

1.2 Other means of identification

Product number -
Other names 2-Pyrrolidinone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Intermediates,Solvents (which become part of product formulation or mixture)
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:616-45-5 SDS

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