Tena

Base Information

• Chemical Name: Tena
• CAS No.: 81919-18-8
• Molecular Formula: C₄₆H₆₂N₄O₈
• Molecular Weight: 799.02
• DSSTox Substance ID: DTXSID801104340
• Nikkaji Number: J23.687J
• Mol file: 81919-18-8.mol

Synonyms:6,6'-(ethylenebis(oxyethyleneimino))bis(17-cyclopropylmethyl)-4,5-epoxymorphinan-3,14-diol;TENA

Chemical Property of Tena

Chemical Property:

• XLogP3: 1.1
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 12
• Rotatable Bond Count: 15
• Exact Mass: 798.45676495
• Heavy Atom Count: 58
• Complexity: 1430

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CC1CN2CCC34C5C(CCC3(C2CC6=C4C(=C(C=C6)O)O5)O)NCCOCCOCCNC7CCC8(C9CC1=C2C8(C7OC2=C(C=C1)O)CCN9CC1CC1)O
• Isomeric SMILES: C1C[C@]2([C@H]3CC4=C5[C@@]2(CCN3CC6CC6)[C@H]([C@@H]1NCCOCCOCCN[C@@H]7CC[C@]8([C@H]9CC1=C2[C@]8([C@H]7OC2=C(C=C1)O)CCN9CC1CC1)O)OC5=C(C=C4)O)O

Technology Process of Tena

There total 2 articles about Tena which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

6β-naltrexamine (67025-97-2) + triethylene glycol di-(p-toluenesulfonate) (19249-03-7) → 1,8-bis(β-naltrexamino)-3,6-dioxaoctane (81919-18-8)

Guidance literature:

With sodium carbonate; In diethylene glycol dimethyl ether; toluene; for 3h; Heating;

DOI:10.1021/jm00349a016

Reference yield:

6β-naltrexamine (67025-97-2) + triethylene glycol di-(p-toluenesulfonate) (19249-03-7) → C33H44N2O8S (81941-17-5) + 1,8-bis(β-naltrexamino)-3,6-dioxaoctane (81919-18-8)

Guidance literature:

With sodium hydrogencarbonate; In diethylene glycol dimethyl ether; toluene; for 3h; Yields of byproduct given; Heating;

DOI:10.1021/jm00349a016

upstream raw materials:

6β-naltrexamine

triethylene glycol di-(p-toluenesulfonate)