2-Anilino-N,N-diethyl-6-methoxybenzamide

Base Information

Chemical Name:2-Anilino-N,N-diethyl-6-methoxybenzamide
CAS No.:83060-84-8
Molecular Formula:C18H22N2O2
Molecular Weight:298.385
Hs Code.:
DSSTox Substance ID:DTXSID40511307
Nikkaji Number:J2.298.252D
Wikidata:Q82370050

Synonyms:2-Anilino-N,N-diethyl-6-methoxybenzamide;83060-84-8;DTXSID40511307

Suppliers and Price of 2-Anilino-N,N-diethyl-6-methoxybenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 2-Anilino-N,N-diethyl-6-methoxybenzamide

Chemical Property:

XLogP3:4.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:298.168127949
Heavy Atom Count:22
Complexity:338

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCN(CC)C(=O)C1=C(C=CC=C1OC)NC2=CC=CC=C2

Technology Process of 2-Anilino-N,N-diethyl-6-methoxybenzamide

There total 6 articles about 2-Anilino-N,N-diethyl-6-methoxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 883726-43-0
N,N-diethyl-N'-(3-methoxyphenyl)-N'-phenylurea

: 83060-84-8
N,N-diethyl-2-anilino-6-methoxybenzamide

: 207802-65-1
N,N-diethyl-2-(3-methoxyanilino)benzamide

Guidance literature:: With lithium diisopropyl amide; In tetrahydrofuran; at 0 - 20 ℃;
DOI:10.1021/ol053162e

Reference yield:

: 108-86-1,52753-63-6
bromobenzene

: 83060-84-8
N,N-diethyl-2-anilino-6-methoxybenzamide

Guidance literature:: Multi-step reaction with 3 steps

1: 89 percent / Pd₂(dba)3; BINAP; t-BuONa / toluene / 90 - 110 °C

2: 99 percent / LHMDS / tetrahydrofuran / 0 - 20 °C

3: 90 percent / LDA / tetrahydrofuran / 0 - 20 °C

With tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; lithium hexamethyldisilazane; sodium t-butanolate; lithium diisopropyl amide; In tetrahydrofuran; toluene; 1: Buchwald-Hartwig reaction / 3: Fries rearrangement;
DOI:10.1021/ol053162e

Reference yield:

: 101-16-6
3-methoxy-N-phenylaniline

: 83060-84-8
N,N-diethyl-2-anilino-6-methoxybenzamide

Guidance literature:: Multi-step reaction with 2 steps

1: 99 percent / LHMDS / tetrahydrofuran / 0 - 20 °C

2: 90 percent / LDA / tetrahydrofuran / 0 - 20 °C

With lithium hexamethyldisilazane; lithium diisopropyl amide; In tetrahydrofuran; 2: Fries rearrangement;
DOI:10.1021/ol053162e