Oxazole, 2-(3,3-dimethyloxiranyl)-4,5-dihydro-4-phenyl-, (4R)-

Base Information

Chemical Name:Oxazole, 2-(3,3-dimethyloxiranyl)-4,5-dihydro-4-phenyl-, (4R)-
CAS No.:832117-30-3
Molecular Formula:C13H15NO2
Molecular Weight:217.268
Hs Code.:
DSSTox Substance ID:DTXSID40461954
Nikkaji Number:J2.124.073G

Synonyms:832117-30-3;Oxazole, 2-(3,3-dimethyloxiranyl)-4,5-dihydro-4-phenyl-, (4R)-;DTXSID40461954

Suppliers and Price of Oxazole, 2-(3,3-dimethyloxiranyl)-4,5-dihydro-4-phenyl-, (4R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Oxazole, 2-(3,3-dimethyloxiranyl)-4,5-dihydro-4-phenyl-, (4R)-

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:217.110278721
Heavy Atom Count:16
Complexity:305

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(C(O1)C2=NC(CO2)C3=CC=CC=C3)C
Isomeric SMILES:CC1(C(O1)C2=N[C@@H](CO2)C3=CC=CC=C3)C

Technology Process of Oxazole, 2-(3,3-dimethyloxiranyl)-4,5-dihydro-4-phenyl-, (4R)-

There total 1 articles about Oxazole, 2-(3,3-dimethyloxiranyl)-4,5-dihydro-4-phenyl-, (4R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67-64-1
acetone

: 221196-89-0
(R)-2-(chloromethyl)-4-phenyl-4,5-dihydrooxazole

: 832117-30-3
(R)-2-(1,2-epoxy-2-methyl)propyl-4-phenyloxazoline

Guidance literature:: With potassium hexamethylsilazane; In tetrahydrofuran; at -78 - -40 ℃; for 8.5h;
DOI:10.1002/anie.200461245

Reference yield: 56.0%

: 603-76-9
1-methylindole

: 832117-30-3
(R)-2-(1,2-epoxy-2-methyl)propyl-4-phenyloxazoline

: 832117-31-4
2-methyl-2-(1-methyl-1H-indol-3-yl)-1((R)-4-phenyl-4,5-dihydrooxazol-2-yl)propan-1-ol

Guidance literature:: With tin(IV) chloride; In dichloromethane; at -78 ℃; for 1.5h;
DOI:10.1002/anie.200461245

Reference yield:

: 832117-30-3
(R)-2-(1,2-epoxy-2-methyl)propyl-4-phenyloxazoline

: 832117-32-5
(R)-(+)-3-[1-methyl-1-(1-methyl-1H-indol-3-yl)ethyl]-5-phenyl-5,6-dihydro[1,4]oxazin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 56 percent / SnCl₄ / CH₂Cl₂ / 1.5 h / -78 °C

2: 90 percent / SeO₂ / CHCl₃ / 4 h / Heating

With selenium(IV) oxide; tin(IV) chloride; In dichloromethane; chloroform;
DOI:10.1002/anie.200461245