Benzenemethanamine, N-[1-(trifluoromethyl)-2-propenyl]-

Base Information

Chemical Name:Benzenemethanamine, N-[1-(trifluoromethyl)-2-propenyl]-
CAS No.:832722-35-7
Molecular Formula:C11H12F3N
Molecular Weight:215.218
Hs Code.:
DSSTox Substance ID:DTXSID20463012

Synonyms:Benzenemethanamine, N-[1-(trifluoromethyl)-2-propenyl]-;832722-35-7;DTXSID20463012;NPWVCBUMBXCWPG-UHFFFAOYSA-N;AKOS015963729

Suppliers and Price of Benzenemethanamine, N-[1-(trifluoromethyl)-2-propenyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Benzenemethanamine, N-[1-(trifluoromethyl)-2-propenyl]-

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:215.09218387
Heavy Atom Count:15
Complexity:195

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C=CC(C(F)(F)F)NCC1=CC=CC=C1

Technology Process of Benzenemethanamine, N-[1-(trifluoromethyl)-2-propenyl]-

There total 1 articles about Benzenemethanamine, N-[1-(trifluoromethyl)-2-propenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 1826-67-1
vinyl magnesium bromide

: 244793-66-6
N-(2,2,2-trifluoro-ethylidene)benzylamine

: 832722-35-7
N-benzyl-N-[1-(trifluoromethyl)prop-2-enyl]amine

Guidance literature:: In tetrahydrofuran; diethyl ether; at 0 ℃; for 2h;
DOI:10.1021/jo0485233

Reference yield: 85.0%

: 108-24-7
acetic anhydride

: 832722-35-7
N-benzyl-N-[1-(trifluoromethyl)prop-2-enyl]amine

: 832722-38-0
N-benzyl-N-[1-(trifluoromethyl)prop-2-enyl]acetamide

Guidance literature:: for 2h; Heating;
DOI:10.1021/jo0485233

Reference yield:

: 832722-35-7
N-benzyl-N-[1-(trifluoromethyl)prop-2-enyl]amine

: N-benzyl-N-(2,2,2-trifluoro-1-oxiranylethyl)amine

Guidance literature:: Multi-step reaction with 3 steps

1.1: 85 percent / 2 h / Heating

2.1: Br₂ / CH₂Cl₂ / 2 h / 0 °C

2.2: 98 percent / aq. NaHSO₃ / CH₂Cl₂

3.1: 80 percent / t-BuOK / tetrahydrofuran / 0 - 20 °C

With potassium tert-butylate; bromine; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jo0485233