2-Pyridinesulfonic acid

Base Information

• Chemical Name: 2-Pyridinesulfonic acid
• CAS No.: 15103-48-7
• Molecular Formula: C5H5NO3S
• Molecular Weight: 159.166
• Hs Code.: 29333990
• European Community (EC) Number: 628-400-6
• NSC Number: 5081
• UNII: 437T6G8UUP
• DSSTox Substance ID: DTXSID00164696
• Nikkaji Number: J1.013.969D
• Mol file: 15103-48-7.mol

Synonyms:pyridine-2-sulfonic acid;15103-48-7;2-Pyridinesulfonic acid;Pyridinesulfonic acid;Pyridine-2-sulfonicacid;alpha-Pyridinesulfonic acid;437T6G8UUP;NSC-5081;2-Pyridinesulfonic acid (8CI)(9CI);Sulfopyridin;NSC 5081;UNII-437T6G8UUP;SCHEMBL34548;.alpha.-Pyridinesulfonic acid;2-Pyridinesulfonic acid, 97%;SCHEMBL3863285;KZVLNAGYSAKYMG-UHFFFAOYSA-;DTXSID00164696;NSC5081;KZVLNAGYSAKYMG-UHFFFAOYSA-N;MFCD00234080;AKOS015854380;CS-W017951;GS-5973;AM100276;FT-0613394;P1647;H10598;A809109;AC-907/25004413;W-205712;InChI=1/C5H5NO3S/c7-10(8,9)5-3-1-2-4-6-5/h1-4H,(H,7,8,9)

Chemical Property of 2-Pyridinesulfonic acid

Chemical Property:

• Melting Point: 244-249 °C
• Refractive Index: 1.576
• PKA: -2.92±0.18(Predicted)
• PSA: 75.64000
• Density: 1.509 g/cm³
• LogP: 1.40910
• Storage Temp.: Inert atmosphere,Room Temperature
• Water Solubility.: almost transparency
• XLogP3: -0.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 158.99901420
• Heavy Atom Count: 10
• Complexity: 193

Purity/Quality:

99% ^*data from raw suppliers

2-Pyridinesulfonic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=NC(=C1)S(=O)(=O)O

Technology Process of 2-Pyridinesulfonic acid

There total 9 articles about 2-Pyridinesulfonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

2-Sulfanylpyridine (2637-34-5,73018-10-7) → pyridine-2-sulfonic acid (15103-48-7)

Guidance literature:

With dihydrogen peroxide; In acetic acid; at 80 ℃;

DOI:10.1002/ejic.200300251

Reference yield:

2-phenylethyl-2-pyridine sulfonate → styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + pyridine-2-sulfonic acid (15103-48-7)

Guidance literature:

at 165.55 - 226.85 ℃; Activation energy; Kinetics;

DOI:10.1002/1097-4601(2000)32:12<771::AID-KIN4>3.0.CO;2-0

Reference yield:

2-p-methoxyphenylethyl-2-pyridine sulfonate → 4-Methoxystyrene (637-69-4,24936-44-5) + pyridine-2-sulfonic acid (15103-48-7)

Guidance literature:

at 125.55 - 226.85 ℃; Activation energy; Kinetics;

DOI:10.1002/1097-4601(2000)32:12<771::AID-KIN4>3.0.CO;2-0

upstream raw materials:

2-Sulfanylpyridine

2-(2-(Pyridin-2-yl)disulfanyl)ethanol

2,2'-dipyridyldisulphide

Downstream raw materials:

1-methyl-2-sulfo-pyridinium betaine

N-(4-methoxyphenyl)pyridin-2-amine

(4-ethoxy-phenyl)-[2]pyridyl-amine

pyrid-2-ylhydrazine

Refernces

• 1、 Lobana, Tarlok S.,Kinoshita, Isamu,Kimura, Kentaro,Nishioka, Takanori,Shiomi, Daisuke,Isobe, Kiyoshi. "Pyridine-2-sulfonates as Versatile Ligands for the Synthesis of Novel Coordinative and Hydrogen-Bonded Supramolecules". . p. 356 - 367. Retrieved 2007/10/03.