2-(Pyridin-2-yldisulfanyl)ethanol

Base Information

• Chemical Name: 2-(Pyridin-2-yldisulfanyl)ethanol
• CAS No.: 111625-28-6
• Molecular Formula: C₇H₉NOS₂
• Molecular Weight: 187.287
• European Community (EC) Number: 631-203-8
• Nikkaji Number: J748.823H
• Mol file: 111625-28-6.mol

Synonyms:111625-28-6;2-(pyridin-2-yldisulfanyl)ethanol;Ethanol, 2-(2-pyridinyldithio)-;(2-pyridyldithio)-PEG1-hydrazine;2-(PYRIDIN-2-YLDISULFANYL)ETHAN-1-OL;2-(2-pyridyldithio)ethanol;2-(2-pyridinyldithio)ethanol;2-(2-(Pyridin-2-yl)disulfanyl)ethanol;(2-pyridyldithio)-PEG1;HydroxyethylpyridYl Disulfide;SCHEMBL126713;2-(2-pyridyldisulfanyl)ethanol;LCZC1216;2-(2-Pyridinyldisulfanyl)ethanol;PORTXTUJPQINJC-UHFFFAOYSA-N;AMY21424;MFCD22551638;AKOS028108752;AT21148;BS-52440;PD171133;HY-136135;CS-0119697;P2819;EN300-4541839;A901855

Chemical Property of 2-(Pyridin-2-yldisulfanyl)ethanol

Chemical Property:

• XLogP3: 1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 187.01255626
• Heavy Atom Count: 11
• Complexity: 102

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=NC(=C1)SSCCO

Technology Process of 2-(Pyridin-2-yldisulfanyl)ethanol

There total 1 articles about 2-(Pyridin-2-yldisulfanyl)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2,2'-dipyridyldisulphide (2127-03-9) + 2-hydroxyethanethiol (60-24-2) → pyridine-2-thione (2637-34-5,646031-56-3) + 2-(2-(Pyridin-2-yl)disulfanyl)ethanol (111625-28-6)

Guidance literature:

With acetic acid; In methanol; at 20 ℃;

DOI:10.1039/c4cc08000a

Reference yield: 100.0%

2-(2-(Pyridin-2-yl)disulfanyl)ethanol (111625-28-6) + [4,6-Di-tert-butyl-2-((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyloxy)-2-methyl-1,3-dioxa-2λ5-phospha-indan-2-yl]-diisopropyl-amine → 2-{2-[4,6-Di-tert-butyl-2-((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyloxy)-2-methyl-1,3-dioxa-2λ5-phospha-indan-2-yloxy]-ethyldisulfanyl}-pyridine (129896-70-4)

Guidance literature:

In dichloromethane; at 25 ℃;

DOI:10.1021/ja00179a048

Reference yield: 96.0%

2-(2-(Pyridin-2-yl)disulfanyl)ethanol (111625-28-6) + 4-Nitrophenyl chloroformate (7693-46-1) → 4-nitrophenyl 2-(2-(pyridin-2-yl)disulfanyl)ethyl carbonate (874302-76-8)

Guidance literature:

With pyridine; In dichloromethane; at 20 ℃; for 15h;

upstream raw materials:

2,2'-dipyridyldisulphide

2-hydroxyethanethiol

Downstream raw materials:

2-{2-[4,6-Di-tert-butyl-2-((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyloxy)-2-methyl-1,3-dioxa-2λ⁵-phospha-indan-2-yloxy]-ethyldisulfanyl}-pyridine

2-{3,5-dichloro-4-[2-(pyridin-2-yldisulfanyl)-ethoxy]-phenylamino}-benzoic acid tert-butyl ester

4-nitrophenyl 2-(2-(pyridin-2-yl)disulfanyl)ethyl carbonate

2-{3,5-dichloro-4-[2-(pyridin-2-yldisulfanyl)-ethoxy]-phenylamino}-benzoic acid