Methyl 4-phenyl-3,4-dihydronaphthalene-2-carboxylate

Base Information

Chemical Name:Methyl 4-phenyl-3,4-dihydronaphthalene-2-carboxylate
CAS No.:83303-57-5
Molecular Formula:C18H16O2
Molecular Weight:264.324
Hs Code.:
DSSTox Substance ID:DTXSID60509281
Nikkaji Number:J2.836.886K

Synonyms:Methyl 4-phenyl-3,4-dihydronaphthalene-2-carboxylate;83303-57-5;DTXSID60509281

Suppliers and Price of Methyl 4-phenyl-3,4-dihydronaphthalene-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Methyl 4-phenyl-3,4-dihydronaphthalene-2-carboxylate

Chemical Property:

XLogP3:4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:264.115029749
Heavy Atom Count:20
Complexity:379

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=CC2=CC=CC=C2C(C1)C3=CC=CC=C3

Technology Process of Methyl 4-phenyl-3,4-dihydronaphthalene-2-carboxylate

There total 5 articles about Methyl 4-phenyl-3,4-dihydronaphthalene-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: methyl 1-(hydroxy(phenyl)methyl)-2-phenylcyclopropane-1-carboxylate

: 83303-57-5
methyl 1,2-dihydro-1-phenylnaphthalene-3-carboxylate

Guidance literature:: With scandium tris(trifluoromethanesulfonate); In 1,2-dichloro-ethane; at 83 ℃; for 1h; Inert atmosphere;
DOI:10.1246/cl.2010.194

Reference yield: 33.0%

: methyl (E)-2-((E)-benzylidene)-4-phenylbut-3-enoate

: 108979-92-6
4-phenyl-3,4-dihydronaphthalene-2-carboxylic acid

: 83303-57-5
methyl 1,2-dihydro-1-phenylnaphthalene-3-carboxylate

Guidance literature:: With trifluorormethanesulfonic acid; In 1,2-dichloro-ethane; at 0 - 50 ℃; for 18h; Inert atmosphere;
DOI:10.1002/adsc.201301169

Reference yield:

: 14578-67-7
4,4-diphenylbutanoic acid

: 83303-57-5
methyl 1,2-dihydro-1-phenylnaphthalene-3-carboxylate

Guidance literature:: Multi-step reaction with 4 steps

1: 83 percent / polyphosphoric acid / 1.) 95-100 deg C; 2.) 105-115 deg C, 2 h; 3.) rt, 8 h

2: 1.) NaH / 1.) benzene, 62-64 deg C, 2 h; 2.) benzene, 70 deg C, 3 h

3: 1.) NaBH₄ / 1.) methanol, 0 deg C, 30-45 min; 2.) methanol, rt, 3-4 h

4: 73 percent / p-toluenesulfonic acid monohydrate, hydroquinone / benzene / Heating

With sodium tetrahydroborate; PPA; sodium hydride; toluene-4-sulfonic acid; hydroquinone; In benzene;