(3S,3aS,5S,9bS)-2,3,5-Triphenyl-2,3,5,9b-tetrahydro-4H-benzo[e]isoindole-1,1,3a-tricarboxylic acid trimethyl ester

Base Information

• Chemical Name: (3S,3aS,5S,9bS)-2,3,5-Triphenyl-2,3,5,9b-tetrahydro-4H-benzo[e]isoindole-1,1,3a-tricarboxylic acid trimethyl ester
• CAS No.: 90625-85-7
• Molecular Formula: C₃₆H₃₃NO₆
• Molecular Weight: 575.661
• Mol file: 90625-85-7.mol

Synonyms:(3S,3aS,5S,9bS)-2,3,5-Triphenyl-2,3,5,9b-tetrahydro-4H-benzo[e]isoindole-1,1,3a-tricarboxylic acid trimethyl ester

Chemical Property of (3S,3aS,5S,9bS)-2,3,5-Triphenyl-2,3,5,9b-tetrahydro-4H-benzo[e]isoindole-1,1,3a-tricarboxylic acid trimethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3S,3aS,5S,9bS)-2,3,5-Triphenyl-2,3,5,9b-tetrahydro-4H-benzo[e]isoindole-1,1,3a-tricarboxylic acid trimethyl ester

There total 4 articles about (3S,3aS,5S,9bS)-2,3,5-Triphenyl-2,3,5,9b-tetrahydro-4H-benzo[e]isoindole-1,1,3a-tricarboxylic acid trimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

dimethyl 1,3-diphenylaziridine-2,2-dicarboxylate (34671-09-5) + methyl 1,2-dihydro-1-phenylnaphthalene-3-carboxylate (83303-57-5) → (3S,3aS,5S,9bS)-2,3,5-Triphenyl-2,3,5,9b-tetrahydro-4H-benzo[e]isoindole-1,1,3a-tricarboxylic acid trimethyl ester (90625-85-7)

Guidance literature:

In 1,3,5-trimethyl-benzene; at 160 - 165 ℃; for 72h;

Reference yield:

dimethyl 2-benzylidenepropanedioate (6626-84-2) → (3S,3aS,5S,9bS)-2,3,5-Triphenyl-2,3,5,9b-tetrahydro-4H-benzo[e]isoindole-1,1,3a-tricarboxylic acid trimethyl ester (90625-85-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 70 percent / 720 h / 60 °C

2: 0.25 h / 170 °C

3: 80 percent / 1,3,5-trimethyl-benzene / 72 h / 160 - 165 °C

In 1,3,5-trimethyl-benzene;

Reference yield:

3,4-Diphenyl-Δ1-1,2,3-triazolin-5,5-dicarbonsaeure-dimethylester (22186-76-1) → (3S,3aS,5S,9bS)-2,3,5-Triphenyl-2,3,5,9b-tetrahydro-4H-benzo[e]isoindole-1,1,3a-tricarboxylic acid trimethyl ester (90625-85-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 0.25 h / 170 °C

2: 80 percent / 1,3,5-trimethyl-benzene / 72 h / 160 - 165 °C

In 1,3,5-trimethyl-benzene;

upstream raw materials:

dimethyl 1,3-diphenylaziridine-2,2-dicarboxylate

methyl 1,2-dihydro-1-phenylnaphthalene-3-carboxylate

dimethyl 2-benzylidenepropanedioate

3,4-Diphenyl-Δ¹-1,2,3-triazolin-5,5-dicarbonsaeure-dimethylester