6beta-Hydroxyprogesterone

Base Information

Chemical Name:6beta-Hydroxyprogesterone
CAS No.:604-19-3
Molecular Formula:C21H30 O3
Molecular Weight:330.467
Hs Code.:
DSSTox Substance ID:DTXSID20975802
Nikkaji Number:J66.990C
Wikidata:Q27131612
Metabolomics Workbench ID:62005
Mol file:604-19-3.mol

Synonyms:6beta-Hydroxyprogesterone;604-19-3;6-beta-Hydroxyprogesterone;6beta-Hydroxy progesterone;BRN 3218996;6-beta-Hydroxypregn-4-ene-3,20-dione;4-PREGNEN-6-BETA-OL-3,20-DIONE;6beta-hydroxydeoxycorticosterone;Pregn-4-ene-3,20-dione, 6-beta-hydroxy-;3,20-dioxopregn-4-en-6beta-ol;U 27605;6beta-hydroxy-4-pregnen-3,20-dione;6beta-hydroxy-4-pregnene-3,20-dione;(6R,8S,9S,10R,13S,14S,17S)-17-acetyl-6-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one;(6beta)-6-hydroxypregn-4-ene-3,20-dione;Pregn-4-ene-3,20-dione, 6.beta.-hydroxy-;4-08-00-02182 (Beilstein Handbook Reference);Pregn-4-ene-3,20-dione, 6-hydroxy-, (6-beta)-;Pregn-4-ene-3,20-dione, 6-hydroxy-, (6.beta.)-;6|A-Hydroxy Progesterone;6-Hydroxypregn-4-ene-3,20-dione;6-?-Hydroxy Progesterone;6.beta.-Hydroxyprogesterone;6.alpha.-Hydroxy-progesterone;SCHEMBL4362728;CHEBI:62117;DTXSID20975802;4-Pregnen-6.beta.-ol-3,20-dione;6-Hydroxypregn-4-ene-3,20-dione #;CS-T-56375;6.beta.-Hydroxypregn-4-ene-3,20-dione;LS-118693;Q27131612

Suppliers and Price of 6beta-Hydroxyprogesterone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6β-HydroxyProgesterone(>80%)
50mg
$ 1455.00

Medical Isotopes, Inc.
6β-Hydroxyprogesterone
5 mg
$ 590.00

Total 15 raw suppliers

Chemical Property of 6beta-Hydroxyprogesterone

Chemical Property:

Vapor Pressure:1.08E-11mmHg at 25°C
Boiling Point:490.8°C at 760 mmHg
Flash Point:264.7°C
PSA：54.37000
Density:1.15g/cm³
LogP:3.69430
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), Methanol (Slightly)
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:330.21949481
Heavy Atom Count:24
Complexity:621

Purity/Quality:

99%, ^*data from raw suppliers

6β-HydroxyProgesterone(>80%) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1CCC2C1(CCC3C2CC(C4=CC(=O)CCC34C)O)C
Isomeric SMILES:CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2C[C@H](C4=CC(=O)CC[C@]34C)O)C
Uses 6β-Hydroxy Progesterone is a metabolite of Progesterone (P755900).

Technology Process of 6beta-Hydroxyprogesterone

There total 14 articles about 6beta-Hydroxyprogesterone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

: 104948-25-6
3-O-benzylpregnenolone

: 604-19-3
6β-hydroxypregn-4-en-3,20-dione

: 85552-32-5
1-((3S,8S,9S,10R,13S,14S,17S)-3-Hydroxy-10,13-dimethyl-hexadecahydro-20-oxa-cyclopropa[5,6]cyclopenta[a]phenanthren-17-yl)-ethanone

: 1-((3S,8S,9S,10R,13S,14S,17S)-3-Benzyloxy-10,13-dimethyl-hexadecahydro-20-oxa-cyclopropa[5,6]cyclopenta[a]phenanthren-17-yl)-ethanone

Guidance literature:: With 3,3-dimethyldioxirane; In acetone; for 18h; Ambient temperature;
DOI:10.1016/S0040-4039(00)60199-5

Reference yield: 8.6%

: 57-83-0
Progesterone

: 16031-66-6
14-hydroxy-4-pregnene-3,20-dione

: 15981-54-1
9α-hydroxypregn-4-ene-3,20-dione

: 604-19-3
6β-hydroxypregn-4-en-3,20-dione

: 604-29-5,604-28-4,123287-83-2
2beta-Hydroxyprogesterone

Guidance literature:: With C_. emersonii; In 1,4-dioxane; for 360h; Further byproducts given; Ambient temperature;
DOI:10.1016/S0031-9422(00)90396-0

Reference yield: 8.6%

: 57-83-0
Progesterone

: 64-85-7
21-Hydroxyprogesterone

: 15981-54-1
9α-hydroxypregn-4-ene-3,20-dione

: 604-19-3
6β-hydroxypregn-4-en-3,20-dione

: 604-29-5,604-28-4,123287-83-2
2beta-Hydroxyprogesterone

Guidance literature:: With C_. emersonii; In 1,4-dioxane; for 360h; Further byproducts given; Ambient temperature;
DOI:10.1016/S0031-9422(00)90396-0