Carbamic acid, (4-ethoxy-2-iodophenyl)-, 1,1-dimethylethyl ester

Base Information

Chemical Name:Carbamic acid, (4-ethoxy-2-iodophenyl)-, 1,1-dimethylethyl ester
CAS No.:835873-11-5
Molecular Formula:C13H18INO3
Molecular Weight:363.195
Hs Code.:
DSSTox Substance ID:DTXSID80479715
Wikidata:Q82313874

Synonyms:835873-11-5;Carbamic acid, (4-ethoxy-2-iodophenyl)-, 1,1-dimethylethyl ester;DTXSID80479715;AKOS015962674

Suppliers and Price of Carbamic acid, (4-ethoxy-2-iodophenyl)-, 1,1-dimethylethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of Carbamic acid, (4-ethoxy-2-iodophenyl)-, 1,1-dimethylethyl ester

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:363.03314
Heavy Atom Count:18
Complexity:278

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC1=CC(=C(C=C1)NC(=O)OC(C)(C)C)I

Technology Process of Carbamic acid, (4-ethoxy-2-iodophenyl)-, 1,1-dimethylethyl ester

There total 1 articles about Carbamic acid, (4-ethoxy-2-iodophenyl)-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 59255-66-2
N-(tert-butoxycarbonyl)-4-ethoxyaniline

: 835873-11-5
(4-ethoxy-2-iodophenyl)carbamic acid tert-butyl ester

Guidance literature:: N-(tert-butoxycarbonyl)-4-ethoxyaniline; With tert.-butyl lithium; In diethyl ether; pentane; at -20 ℃; for 3h;

With 1,2-Diiodoethane; In diethyl ether; pentane; at -78 - 20 ℃; for 16h;
DOI:10.1021/ol0477226

Reference yield: 62.0%

: 835873-11-5
(4-ethoxy-2-iodophenyl)carbamic acid tert-butyl ester

: 90446-67-6
4-((tert-butyldimethylsilyl)oxy)benzoyl chloride

: 835873-12-6
[4-(tert-butyldimethylsilanyloxy)-benzoyl]-(4-ethoxy-2-iodophenyl)carbamic acid tert-butyl ester

Guidance literature:: With dmap; triethylamine; In chloroform; for 1h; Heating;
DOI:10.1021/ol0477226

Reference yield:

: 835873-11-5
(4-ethoxy-2-iodophenyl)carbamic acid tert-butyl ester

: 835873-13-7
(4-ethoxy-2-iodophenyl)-(4-hydroxybenzoyl)carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 62 percent / triethylamine; 4-(dimethylamino)pyridine / CHCl₃ / 1 h / Heating

2: 93 percent / Bu₄NF / tetrahydrofuran / 0.17 h / 20 °C

With dmap; tetrabutyl ammonium fluoride; triethylamine; In tetrahydrofuran; chloroform;
DOI:10.1021/ol0477226