2-(Chloromethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Base Information

Chemical Name:2-(Chloromethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS No.:83622-42-8
Molecular Formula:C7H14BClO2
Molecular Weight:176.451
Hs Code.:2934999090
DSSTox Substance ID:DTXSID60456125
Nikkaji Number:J1.576.481C
Wikidata:Q72453828
Mol file:83622-42-8.mol

Synonyms:83622-42-8;2-(chloromethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;(Chloromethyl)boronic Acid Pinacol Ester;1,3,2-Dioxaborolane, 2-(chloromethyl)-4,4,5,5-tetramethyl-;MFCD12405514;C7H14BClO2;SCHEMBL1691193;DTXSID60456125;ABFNBZSUTILCRK-UHFFFAOYSA-N;BCP13674;AKOS016012210;CS-W006387;DS-6867;SY022384;BB 0260989;FT-0749962;N10604;A852983;2-(Chloromethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Suppliers and Price of 2-(Chloromethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(Chloromethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
250mg
$ 55.00

Crysdot
2-(Chloromethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 95+%
10g
$ 230.00

Crysdot
2-(Chloromethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 95+%
25g
$ 479.00

ChemScene
2-(Chloromethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane ≥98.0%
25g
$ 293.00

ChemScene
2-(Chloromethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane ≥98.0%
5g
$ 69.00

ChemScene
2-(Chloromethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane ≥98.0%
10g
$ 135.00

Chemenu
2-(Chloromethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 97%
5g
$ 72.00

Chemenu
2-(Chloromethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 97%
25g
$ 278.00

Chemenu
2-(Chloromethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 97%
100g
$ 594.00

Chemenu
2-(Chloromethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 97%
10g
$ 135.00

Total 24 raw suppliers

Chemical Property of 2-(Chloromethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Chemical Property:

Boiling Point:81℃ (14 Torr)
PSA：18.46000
Density:1.02±0.1 g/cm3(Predicted)
LogP:2.27490
Storage Temp.:Inert atmosphere,Store in freezer, under -20°C
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:176.0775375
Heavy Atom Count:11
Complexity:143

Purity/Quality:

99%, ^*data from raw suppliers

2-(Chloromethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:B1(OC(C(O1)(C)C)(C)C)CCl

Technology Process of 2-(Chloromethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

There total 8 articles about 2-(Chloromethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 83622-41-7
pinacol dichloromethylboronic ester

: 83622-42-8
2-(chloromethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Guidance literature:: With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In benzene; (Ar); Bu3SnH added to B compd. soln., AIBN added, stirred for 24 h at room temp.; fractional distn.; elem. anal.;
DOI:10.1016/S0022-328X(00)85850-7

Reference yield: 89.7%

: 593-71-5
Chloroiodomethane

: 61676-62-8
2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

: 83622-42-8
2-(chloromethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Guidance literature:: Chloroiodomethane; 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere;

With chloro-trimethyl-silane; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 24.1667h; Inert atmosphere;
DOI:10.1021/ja308613b

Reference yield: 81.0%

: 76-09-5
2,3-dimethyl-2,3-butane diol

: 83622-42-8
2-(chloromethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Guidance literature:: Chloroiodomethane; With n-butyllithium; Triisopropyl borate; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 2.83333h;

2,3-dimethyl-2,3-butane diol; With hydrogenchloride; In tetrahydrofuran; hexane; ethyl acetate; at 0 - 20 ℃; for 0.666667h;