(2S,4S)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylic acid

Base Information

Chemical Name:(2S,4S)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylic acid
CAS No.:83623-93-2
Molecular Formula:C11H19NO5
Molecular Weight:245.276
Hs Code.:2933990090
European Community (EC) Number:862-506-5
DSSTox Substance ID:DTXSID00570233
Wikidata:Q72510267
Mol file:83623-93-2.mol

Synonyms:83623-93-2;(2S,4S)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylic acid;CIS-1-N-BOC-4-METHOXY-L-PROLINE;(2S,4S)-4-Methoxy-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester;(2S,4S)-1-[(tert-butoxy)carbonyl]-4-methoxypyrrolidine-2-carboxylic acid;(2S,4S)-1-(tert-Butoxycarbonyl)-4-methoxy-pyrrolidine-2-carboxylic acid;(2S,4S)-4-methoxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid;MFCD11501217;SCHEMBL239963;DTXSID00570233;COHIMMPWCAHSFN-YUMQZZPRSA-N;(2S,4S)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylicacid;AKOS015998810;AC-30960;AS-52785;CS-0053415;EN300-209942;A848464;(4S)-1-(tert-Butoxycarbonyl)-4-methoxy-L-proline;4-Methoxy-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester;E(3)E(1/2)-1-N-BOC-4-(1/4)xNo>>u-L- not degrees +/-Ea;(2S pound not4S)-4-Methoxy-pyrrolidine-1 pound not2-dicarboxylic acid 1-tert-butyl ester

Suppliers and Price of (2S,4S)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
(2S,4S)-1-(tert-Butoxycarbonyl)-4-methoxy-pyrrolidine-2-carboxylicacid 97%
10g
$ 2293.00

Matrix Scientific
(2S,4S)-1-(tert-Butoxycarbonyl)-4-methoxy-pyrrolidine-2-carboxylicacid 97%
5g
$ 1491.00

Matrix Scientific
(2S,4S)-1-(tert-Butoxycarbonyl)-4-methoxy-pyrrolidine-2-carboxylicacid 97%
1g
$ 425.00

Crysdot
(2S,4S)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylicacid 97%
1g
$ 421.00

ChemScene
(2S,4S)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylicacid
100mg
$ 113.00

ChemScene
(2S,4S)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylicacid
250mg
$ 188.00

Chemenu
(2S,4S)-1-(tert-Butoxycarbonyl)-4-methoxy-pyrrolidine-2-carboxylicacid 97%
1g
$ 397.00

AstaTech
CIS-1-N-BOC-4-METHOXY-L-PROLINE 97%
0.25 / G
$ 270.00

AstaTech
CIS-1-N-BOC-4-METHOXY-L-PROLINE 97%
5 / G
$ 2276.00

AstaTech
CIS-1-N-BOC-4-METHOXY-L-PROLINE 97%
1 / G
$ 760.00

Total 24 raw suppliers

Chemical Property of (2S,4S)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylic acid

Chemical Property:

Boiling Point:362.0±42.0 °C(Predicted)
PKA:3.75±0.40(Predicted)
PSA：76.07000
Density:1.20±0.1 g/cm3(Predicted)
LogP:1.03330
Storage Temp.:2-8°C
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:245.12632271
Heavy Atom Count:17
Complexity:310

Purity/Quality:

98% ^*data from raw suppliers

(2S,4S)-1-(tert-Butoxycarbonyl)-4-methoxy-pyrrolidine-2-carboxylicacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CC(CC1C(=O)O)OC
Isomeric SMILES:CC(C)(C)OC(=O)N1C[C@H](C[C@H]1C(=O)O)OC

Technology Process of (2S,4S)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylic acid

There total 1 articles about (2S,4S)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.3%

: 87691-27-8,946610-68-0
N-tert-butoxycarbonyl-L-cis-4-hydroxyproline

: 74-88-4
methyl iodide

: 83623-93-2
(2S,4S)-1-[(tert-butoxy)carbonyl]-4-methoxypyrrolidine-2-carboxylic acid

Guidance literature:: With hydrogenchloride; sodium hydroxide; In N-methyl-acetamide; methanol; hexane; water;

Reference yield: 97.0%

: 99-73-0,132309-76-3
para-bromophenacyl bromide

: 83623-93-2
(2S,4S)-1-[(tert-butoxy)carbonyl]-4-methoxypyrrolidine-2-carboxylic acid

: 4-(4-bromo-phenyl)-2-((2S,4S)-4-methoxy-pyrrolidin-2-yl)-1H-imidazole di-hydrochloride

Guidance literature:: para-bromophenacyl bromide; (2S,4S)-1-[(tert-butoxy)carbonyl]-4-methoxypyrrolidine-2-carboxylic acid; With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 35 ℃; for 3h; Inert atmosphere;

With ammonium acetate; In dichloromethane; toluene; at 95 ℃; Inert atmosphere;

With hydrogenchloride; In 1,4-dioxane; dichloromethane; toluene; for 1h; Inert atmosphere;