4-(3,4-Dimethylphenyl)-1,3-thiazol-2-amine

Base Information

• Chemical Name: 4-(3,4-Dimethylphenyl)-1,3-thiazol-2-amine
• CAS No.: 104296-00-6
• Molecular Formula: C11H12 N2 S
• Molecular Weight: 204.296
• Hs Code.: 2934100090
• European Community (EC) Number: 672-118-6
• DSSTox Substance ID: DTXSID10352663
• Wikidata: Q82129920
• Mol file: 104296-00-6.mol

Synonyms:104296-00-6;4-(3,4-dimethylphenyl)-1,3-thiazol-2-amine;4-(3,4-Dimethyl-phenyl)-thiazol-2-ylamine;4-(3,4-dimethylphenyl)thiazol-2-amine;4-(3,4-dimethylphenyl)thiazol-2-ylamine;Oprea1_693974;SCHEMBL7236001;DTXSID10352663;YAHPYUWCTUAXGT-UHFFFAOYSA-N;HMS3428J11;BBL013873;MFCD00806191;STK410915;AKOS000115516;AB07324;CCG-109055;4-(3,4-dimethylphenyl)-2-thiazolamine;LS-01137;2-amino-4-(3,4-dimethyl-phenyl)-thiazole;4-(3,4-dimethylphenyl)-thiazol-2-ylamine;BB 0237385;EU-0075098;FT-0642565;EN300-02248;A800951;J-001140;Z48847551;F3098-3688

Chemical Property of 4-(3,4-Dimethylphenyl)-1,3-thiazol-2-amine

Chemical Property:

• Vapor Pressure: 7.42E-06mmHg at 25°C
• Boiling Point: 376.1°Cat760mmHg
• PKA: 4.52±0.10(Predicted)
• Flash Point: 181.3°C
• PSA: 67.15000
• Density: 1.185g/cm³
• LogP: 3.59030
• XLogP3: 3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 204.07211956
• Heavy Atom Count: 14
• Complexity: 198

Purity/Quality:

98%min ^*data from raw suppliers

4-(3,4-Dimethyl-phenyl)-thiazol-2-ylamine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C=C(C=C1)C2=CSC(=N2)N)C

Technology Process of 4-(3,4-Dimethylphenyl)-1,3-thiazol-2-amine

There total 3 articles about 4-(3,4-Dimethylphenyl)-1,3-thiazol-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C16H20N2O2S → N-(2-hydroxybenzylidene)anthranilic acid (104296-00-6)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; for 1h;

DOI:10.1016/j.bmc.2021.116242

Reference yield: 100.0%

→ N-(2-hydroxybenzylidene)anthranilic acid (104296-00-6)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; for 1h;

Reference yield:

thiourea (17356-08-0) + 3,4-dimethylacetophenone (3637-01-2) → N-(2-hydroxybenzylidene)anthranilic acid (104296-00-6)

Guidance literature:

With iodine; benzene;

upstream raw materials:

thiourea

3,4-dimethylacetophenone

Downstream raw materials:

2-[4-(3,4-dimethyl-phenyl)-thiazol-2-ylaminocarbonyl]-benzoic acid

Refernces

• 1、 -. "VACCINE ADJUVANT". Page/Page column 71-72. . Retrieved 2020/06/10.