Acetamide, N-(4-fluorophenyl)-N-hydroxy-

Base Information

Chemical Name:Acetamide, N-(4-fluorophenyl)-N-hydroxy-
CAS No.:38373-19-2
Molecular Formula:C8H8FNO2
Molecular Weight:169.155
Hs Code.:2924299090
Mol file:38373-19-2.mol

Synonyms:Acetamide,N-(4-fluorophenyl)-N-hydroxy;N-(4-FLUOROPHENYL)-N-HYDROXY-ACETAMIDE;

Suppliers and Price of Acetamide, N-(4-fluorophenyl)-N-hydroxy-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Acetamide, N-(4-fluorophenyl)-N-hydroxy-

Chemical Property:

Vapor Pressure:0.00107mmHg at 25°C
Boiling Point:288.6°Cat760mmHg
Flash Point:128.3°C
PSA：40.54000
Density:1.339g/cm³
LogP:1.56780

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Acetamide, N-(4-fluorophenyl)-N-hydroxy-

There total 4 articles about Acetamide, N-(4-fluorophenyl)-N-hydroxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 406-00-8
4-fluoro-N-hydroxyaniline

: 75-36-5
acetyl chloride

: 38373-19-2
N-(4-fluorophenyl)-N-hydroxyacetamide

Guidance literature:: With sodium hydrogencarbonate; In diethyl ether; at 0 ℃; Inert atmosphere;
DOI:10.1002/anie.201409375

Reference yield: 53.4%

: 350-46-9,178603-76-4
4-Fluoronitrobenzene

: 38373-19-2
N-(4-fluorophenyl)-N-hydroxyacetamide

Guidance literature:: 4-Fluoronitrobenzene; With ammonium chloride; zinc;

acetylate;
DOI:10.1016/j.tetlet.2015.07.070

Reference yield:

: 350-46-9,178603-76-4
4-Fluoronitrobenzene

: 38373-19-2
N-(4-fluorophenyl)-N-hydroxyacetamide

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine hydrate; 5% rhodium-on-charcoal / tetrahydrofuran / 2 h / 0 °C / Inert atmosphere

2: sodium hydrogencarbonate / diethyl ether / 0 °C / Inert atmosphere

With 5% rhodium-on-charcoal; sodium hydrogencarbonate; hydrazine hydrate; In tetrahydrofuran; diethyl ether;
DOI:10.1002/anie.201409375