2,6-Difluoro-4-hydrazinylpyridine

Base Information

• Chemical Name: 2,6-Difluoro-4-hydrazinylpyridine
• CAS No.: 837364-94-0
• Molecular Formula: C₅H₅F₂N₃
• Molecular Weight: 145.112
• Hs Code.: 2933399990
• DSSTox Substance ID: DTXSID10479263
• Nikkaji Number: J2.134.033B
• Wikidata: Q82313245
• Mol file: 837364-94-0.mol

Synonyms:2,6-difluoro-4-hydrazinylpyridine;837364-94-0;2,6-Difluoro-4-hydrazinopyridine;(2,6-difluoropyridin-4-yl)hydrazine;(2,6-Difluoro-pyridin-4-yl)-hydrazine;MFCD08436095;SCHEMBL3867073;DTXSID10479263;YDUYJJIXZAXMIJ-UHFFFAOYSA-N;AKOS006336382;DS-9029;SB75426;SY115286;2 pound not6-Difluoro-4-hydrazinylpyridine;CS-0157660;C76675

Chemical Property of 2,6-Difluoro-4-hydrazinylpyridine

Chemical Property:

• PSA: 50.94000
• LogP: 1.41870
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• XLogP3: 1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1
• Exact Mass: 145.04515350
• Heavy Atom Count: 10
• Complexity: 101

Purity/Quality:

99% ^*data from raw suppliers

2,6-Difluoro-4-hydrazinylpyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C=C(N=C1F)F)NN

Technology Process of 2,6-Difluoro-4-hydrazinylpyridine

There total 1 articles about 2,6-Difluoro-4-hydrazinylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2,4,6-trifluoropyridine (3512-17-2) → 2,6-difluoro-4-hydrazinylpyridine (837364-94-0)

Guidance literature:

With hydrazine hydrate; In tetrahydrofuran; at 50 ℃; for 2h;

DOI:10.1021/jo047962z

upstream raw materials:

2,4,6-trifluoropyridine

Refernces

• 1、 -. "AMINOPYRAZOLES AS SELECTIVE JANUS KINASE INHIBITORS". Page/Page column 21-22. . Retrieved 2018/07/05.
• 2、 -. "Substituted pyridines". Page/Page column 5. . Retrieved 2008/06/13.