Benzenamine, 2-iodo-N-[(4-methylphenyl)methylene]-

Base Information

• Chemical Name: Benzenamine, 2-iodo-N-[(4-methylphenyl)methylene]-
• CAS No.: 838828-39-0
• Molecular Formula: C14H12IN
• Molecular Weight: 321.16
• Mol file: 838828-39-0.mol

Synonyms:

Chemical Property of Benzenamine, 2-iodo-N-[(4-methylphenyl)methylene]-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzenamine, 2-iodo-N-[(4-methylphenyl)methylene]-

There total 1 articles about Benzenamine, 2-iodo-N-[(4-methylphenyl)methylene]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

2-iodophenylamine (615-43-0) + 4-methyl-benzaldehyde (104-87-0) → N-(4-methylbenzylidene)-2-iodoaniline (838828-39-0)

Guidance literature:

With toluene-4-sulfonic acid; In benzene; at 20 ℃; for 168h; Molecular sieve;

DOI:10.1021/ol800202u

Reference yield: 70.0%

[2,2]bipyridinyl (366-18-7) + Pd2(dba)4 + N-(4-methylbenzylidene)-2-iodoaniline (838828-39-0) → [PdI(2,2'-bipyridine)(C6H4NCH(p-tolyl))] (1192558-98-7)

Guidance literature:

In toluene; (N2); addn. of IC6H4NCHC6H4CH3 and bipy with 10 min interval to suspn. of Pd2(dba)3*dba in toluene; stirring for 3 h; removal of solvent under vac. to dryness; stirring with CH2Cl2; filtration; concn. of filtrate; addn. of Et2O; filtration, washing with Et2O; drying by suction; elem. anal.;

DOI:10.1021/om900616v

Reference yield: 31.0%

Pd2(dba)4 + N-(4-methylbenzylidene)-2-iodoaniline (838828-39-0) + 4,4'-di-tert-butyl-2,2'-bipyridine (72914-19-3) → [PdI(4,4'-di-tert-butyl-2,2'-bipyridine)(C6H4NCH(p-tolyl))] (1192558-99-8)

Guidance literature:

In toluene; (N2); addn. of IC6H4NCHC6H4CH3 and 4,4'-di-tert-butyl-bipy with 10 min interval to suspn. of Pd2(dba)3*dba in toluene; stirring for 1.5 h; removal of solvent (vac.) to dryness; stirring with CH2Cl2; filtration; concn. to dryness; addn. of cold Et2O (0°C) and n-hexane (0°C); pptn., reflux in C6H14 for 15 min; hot filtration, washing (hexane); drying by suction; elem. anal.;

DOI:10.1021/om900616v

upstream raw materials:

2-iodophenylamine

4-methyl-benzaldehyde

Downstream raw materials:

[PdI(2,2'-bipyridine)(C₆H₄NCH(p-tolyl))]

[PdI(4,4'-di-tert-butyl-2,2'-bipyridine)(C₆H₄NCH(p-tolyl))]

2-iodo-N-(4-methylbenzyl)aniline

2-iodo-N-methyl-N-(4-methylbenzyl)aniline