Technology Process of Phellopterin
There total 7 articles about Phellopterin which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium carbonate;
In
N,N-dimethyl-formamide;
for 1h;
Reflux;
Inert atmosphere;
DOI:10.1016/j.bmc.2011.12.002
- Guidance literature:
-
Multi-step reaction with 4 steps
1: nitric acid; acetic acid / 20 °C
2: hydrogenchloride; zinc / water; acetone / 20 °C
3: potassium carbonate / N,N-dimethyl-formamide / 2 h / Inert atmosphere; Reflux
4: potassium carbonate / N,N-dimethyl-formamide / 1 h / Reflux; Inert atmosphere
With
hydrogenchloride; nitric acid; potassium carbonate; acetic acid; zinc;
In
water; N,N-dimethyl-formamide; acetone;
DOI:10.1016/j.bmc.2011.12.002
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: boron tribromide / dichloromethane / 4 h / 20 °C / Inert atmosphere
1.2: 1 h
2.1: nitric acid; acetic acid / 20 °C
3.1: hydrogenchloride; zinc / water; acetone / 20 °C
4.1: potassium carbonate / N,N-dimethyl-formamide / 2 h / Inert atmosphere; Reflux
5.1: potassium carbonate / N,N-dimethyl-formamide / 1 h / Reflux; Inert atmosphere
With
hydrogenchloride; nitric acid; boron tribromide; potassium carbonate; acetic acid; zinc;
In
dichloromethane; water; N,N-dimethyl-formamide; acetone;
DOI:10.1016/j.bmc.2011.12.002
