5-[(2-Methylphenoxy)methyl]-1,3,4-thiadiazol-2-amine

Base Information

Chemical Name:5-[(2-Methylphenoxy)methyl]-1,3,4-thiadiazol-2-amine
CAS No.:84138-75-0
Molecular Formula:C10H11N3OS
Molecular Weight:221.283
Hs Code.:2934999090
DSSTox Substance ID:DTXSID90356962
Nikkaji Number:J1.590.786J
Wikidata:Q82136612
Mol file:84138-75-0.mol

Synonyms:84138-75-0;5-[(2-methylphenoxy)methyl]-1,3,4-thiadiazol-2-amine;5-o-Tolyloxymethyl-[1,3,4]thiadiazol-2-ylamine;5-((O-TOLYLOXY)METHYL)-1,3,4-THIADIAZOL-2-AMINE;Cambridge id 6043168;TimTec1_006804;Oprea1_542719;Oprea1_732949;SCHEMBL3729107;DTXSID90356962;HMS1553F06;BBL002932;STK094137;AKOS000303223;AS-38455;BB 0218593;CS-0313863;FT-0705936

Suppliers and Price of 5-[(2-Methylphenoxy)methyl]-1,3,4-thiadiazol-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-((O-Tolyloxy)methyl)-1,3,4-thiadiazol-2-amine
10mg
$ 45.00

Matrix Scientific
5-o-Tolyloxymethyl-[1,3,4]thiadiazol-2-ylamine
500mg
$ 200.00

Matrix Scientific
5-o-Tolyloxymethyl-[1,3,4]thiadiazol-2-ylamine
1g
$ 308.00

Crysdot
5-((o-tolyloxy)Methyl)-1,3,4-thiadiazol-2-amine 95+%
5g
$ 874.00

Alichem
5-((O-tolyloxy)methyl)-1,3,4-thiadiazol-2-amine
250mg
$ 229.69

Alichem
5-((O-tolyloxy)methyl)-1,3,4-thiadiazol-2-amine
1g
$ 568.14

AK Scientific
5-o-Tolyloxymethyl-[1,3,4]thiadiazol-2-ylamine
1g
$ 465.00

Total 4 raw suppliers

Chemical Property of 5-[(2-Methylphenoxy)methyl]-1,3,4-thiadiazol-2-amine

Chemical Property:

PSA：90.00000
LogP:1.93780
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:221.06228316
Heavy Atom Count:15
Complexity:205

Purity/Quality:

98%min ^*data from raw suppliers

5-((O-Tolyloxy)methyl)-1,3,4-thiadiazol-2-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=CC=C1OCC2=NN=C(S2)N

Technology Process of 5-[(2-Methylphenoxy)methyl]-1,3,4-thiadiazol-2-amine

There total 7 articles about 5-[(2-Methylphenoxy)methyl]-1,3,4-thiadiazol-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 143540-89-0
2-{[(2-methylphenyl)oxy]acetyl}hydrazinecarbothioamide

: 84138-75-0
2-amino-5-(2-methylphenoxymethyl)-1,3,4-thiadiazole

Guidance literature:: DOI:10.1271/bbb1961.47.103

Reference yield: 65.0%

: 1878-49-5
o-methylphenoxyacetic acid

: 79-19-6
thiosemicarbazide

: 84138-75-0
2-amino-5-(2-methylphenoxymethyl)-1,3,4-thiadiazole

Guidance literature:: o-methylphenoxyacetic acid; thiosemicarbazide; With trichlorophosphate; for 0.5h; Reflux;

With water; for 4h; Reflux;

Reference yield:

: 95-48-7,77504-84-8
ortho-cresol

: 84138-75-0
2-amino-5-(2-methylphenoxymethyl)-1,3,4-thiadiazole

Guidance literature:: Multi-step reaction with 4 steps

1: potassium carbonate / acetone / 8 h / Reflux

2: hydrazine hydrate / methanol / 1 h / 20 °C

3: ethanol / 4 h / Reflux

4: phosphoric acid / 2 h / 120 °C

With ethanol; phosphoric acid; potassium carbonate; hydrazine hydrate; In methanol; acetone;
DOI:10.1016/j.bmc.2010.11.034