2,6-Di-tert-butyl-4-[2-(methylsulfanyl)-1H-imidazol-5-yl]phenol

Base Information

Chemical Name:2,6-Di-tert-butyl-4-[2-(methylsulfanyl)-1H-imidazol-5-yl]phenol
CAS No.:84203-46-3
Molecular Formula:C18H26N2OS
Molecular Weight:318.483
Hs Code.:
DSSTox Substance ID:DTXSID20518339
Wikidata:Q82380976

Synonyms:84203-46-3;SCHEMBL10791796;DTXSID20518339;PHPVPNDIKPXLHJ-UHFFFAOYSA-N;2,6-Di-tert-butyl-4-[2-(methylsulfanyl)-1H-imidazol-5-yl]phenol;4-(3,5-di-tert-butyl-4-hydroxyphenyl)-2-methylthioimidazole

Suppliers and Price of 2,6-Di-tert-butyl-4-[2-(methylsulfanyl)-1H-imidazol-5-yl]phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2,6-Di-tert-butyl-4-[2-(methylsulfanyl)-1H-imidazol-5-yl]phenol

Chemical Property:

XLogP3:5.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:318.17658463
Heavy Atom Count:22
Complexity:350

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)C2=CN=C(N2)SC

Technology Process of 2,6-Di-tert-butyl-4-[2-(methylsulfanyl)-1H-imidazol-5-yl]phenol

There total 4 articles about 2,6-Di-tert-butyl-4-[2-(methylsulfanyl)-1H-imidazol-5-yl]phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

: 84203-45-2
4-(3,5-di-tert-butyl-4-hydroxyphenyl)-2-thioxo-4-imidazoline

: 74-88-4
methyl iodide

: 84203-46-3
4-(3,5-di-tert-butyl-4-hydroxyphenyl)-2-methylthioimidazole

Guidance literature:: With potassium carbonate; In acetone; for 1h; Ambient temperature;
DOI:10.1248/cpb.32.152

Reference yield:

: 14386-64-2
2-bromo-1-(3,5-di-tert-butyl-4-hydroxyphenyl)ethanone

: 84203-46-3
4-(3,5-di-tert-butyl-4-hydroxyphenyl)-2-methylthioimidazole

Guidance literature:: Multi-step reaction with 4 steps

1: sodium azide / H₂O; acetone / 1 h / Ambient temperature

2: H₂, HCl / Pd-C / methanol

3: 57.8 percent / HCl / H₂O; ethanol / 1.5h, r.t., 2h, reflux

4: 39 percent / K₂CO₃ / acetone / 1 h / Ambient temperature

With hydrogenchloride; sodium azide; hydrogen; potassium carbonate; palladium on activated charcoal; In methanol; ethanol; water; acetone;
DOI:10.1248/cpb.32.152

Reference yield:

: 870789-66-5
2-azido-1-[3,5-di(tert-butyl)-4-hydroxy-phenyl]-ethan-1-one

: 84203-46-3
4-(3,5-di-tert-butyl-4-hydroxyphenyl)-2-methylthioimidazole

Guidance literature:: Multi-step reaction with 3 steps

1: H₂, HCl / Pd-C / methanol

2: 57.8 percent / HCl / H₂O; ethanol / 1.5h, r.t., 2h, reflux

3: 39 percent / K₂CO₃ / acetone / 1 h / Ambient temperature

With hydrogenchloride; hydrogen; potassium carbonate; palladium on activated charcoal; In methanol; ethanol; water; acetone;
DOI:10.1248/cpb.32.152