2,6-Di-tert-butyl-4-{2-[(propan-2-yl)sulfanyl]-1,3-thiazol-4-yl}phenol

Base Information

Chemical Name:2,6-Di-tert-butyl-4-{2-[(propan-2-yl)sulfanyl]-1,3-thiazol-4-yl}phenol
CAS No.:84217-68-5
Molecular Formula:C20H29NOS2
Molecular Weight:363.58000
Hs Code.:
DSSTox Substance ID:DTXSID10518343
Wikidata:Q82380986

Synonyms:84217-68-5;SCHEMBL10791534;DTXSID10518343;2,6-Di-tert-butyl-4-{2-[(propan-2-yl)sulfanyl]-1,3-thiazol-4-yl}phenol

Suppliers and Price of 2,6-Di-tert-butyl-4-{2-[(propan-2-yl)sulfanyl]-1,3-thiazol-4-yl}phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2,6-Di-tert-butyl-4-{2-[(propan-2-yl)sulfanyl]-1,3-thiazol-4-yl}phenol

Chemical Property:

PSA：86.66000
LogP:6.61120
XLogP3:7.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:363.16905690
Heavy Atom Count:24
Complexity:389

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)SC1=NC(=CS1)C2=CC(=C(C(=C2)C(C)(C)C)O)C(C)(C)C

Technology Process of 2,6-Di-tert-butyl-4-{2-[(propan-2-yl)sulfanyl]-1,3-thiazol-4-yl}phenol

There total 3 articles about 2,6-Di-tert-butyl-4-{2-[(propan-2-yl)sulfanyl]-1,3-thiazol-4-yl}phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 75-30-9
2-iodo-propane

: 84217-42-5
4-(3,5-di-tert-butyl-4-hydroxyphenyl)-2-mercaptothiazole

: 84217-68-5
4-(3,5-di-tert-butyl-4-hydroxyphenyl)-2-isopropylthiothiazole

Guidance literature:: With sodium; In methanol; at 0 - 5 ℃; for 0.5h;
DOI:10.1248/cpb.32.152

Reference yield:

: 14386-64-2
2-bromo-1-(3,5-di-tert-butyl-4-hydroxyphenyl)ethanone

: 84217-68-5
4-(3,5-di-tert-butyl-4-hydroxyphenyl)-2-isopropylthiothiazole

Guidance literature:: Multi-step reaction with 2 steps

1: 56.7 percent / ethanol / Ambient temperature

2: 70 percent / sodium / methanol / 0.5 h / 0 - 5 °C

With sodium; In methanol; ethanol;
DOI:10.1248/cpb.32.152