6-[3-Amino-4-(morpholin-4-yl)phenyl]-4,5-dihydropyridazin-3(2H)-one

Base Information

Chemical Name:6-[3-Amino-4-(morpholin-4-yl)phenyl]-4,5-dihydropyridazin-3(2H)-one
CAS No.:84313-90-6
Molecular Formula:C14H18N4O2
Molecular Weight:274.323
Hs Code.:
DSSTox Substance ID:DTXSID20603178
Nikkaji Number:J457.255F
Wikidata:Q82500474

Synonyms:84313-90-6;SCHEMBL10763963;DTXSID20603178;6-[3-Amino-4-(morpholin-4-yl)phenyl]-4,5-dihydropyridazin-3(2H)-one

Suppliers and Price of 6-[3-Amino-4-(morpholin-4-yl)phenyl]-4,5-dihydropyridazin-3(2H)-one

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6-[3-Amino-4-(morpholin-4-yl)phenyl]-4,5-dihydropyridazin-3(2H)-one

Chemical Property:

XLogP3:0
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:274.14297583
Heavy Atom Count:20
Complexity:393

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC(=O)NN=C1C2=CC(=C(C=C2)N3CCOCC3)N

Technology Process of 6-[3-Amino-4-(morpholin-4-yl)phenyl]-4,5-dihydropyridazin-3(2H)-one

There total 4 articles about 6-[3-Amino-4-(morpholin-4-yl)phenyl]-4,5-dihydropyridazin-3(2H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 84314-04-5
4-(4-chloro-3-nitrophenyl)-4-oxobutanoic acid

: 84313-90-6
6-(3-amino-4-morpholino-phenyl)-4,5-dihydro-3(2H)-pyridazinone

Guidance literature:: Multi-step reaction with 3 steps

1: 95 percent / iPr₂NEt / dimethylsulfoxide / 3 h / 80 °C

2: 70 percent / H₂ / 5percent Pd/C / dioxane / Ambient temperature

3: H₂NNH₂*H₂O / ethanol / 2 h / Heating

With hydrogen; hydrazine hydrate; N-ethyl-N,N-diisopropylamine; palladium on activated charcoal; In 1,4-dioxane; ethanol; dimethyl sulfoxide;
DOI:10.1016/0223-5234(91)90121-3

Reference yield:

: 56872-65-2
3-(3-nitro-4-morpholino-benzoyl)-propionic acid

: 84313-90-6
6-(3-amino-4-morpholino-phenyl)-4,5-dihydro-3(2H)-pyridazinone

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / H₂ / 5percent Pd/C / dioxane / Ambient temperature

2: H₂NNH₂*H₂O / ethanol / 2 h / Heating

With hydrogen; hydrazine hydrate; palladium on activated charcoal; In 1,4-dioxane; ethanol;
DOI:10.1016/0223-5234(91)90121-3