Technology Process of Acetamide,
N-[2-(4-morpholinyl)-5-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl)phenyl]-
There total 4 articles about Acetamide,
N-[2-(4-morpholinyl)-5-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl)phenyl]- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
N-ethyl-N,N-diisopropylamine;
In
N,N-dimethyl-formamide;
for 48h;
Ambient temperature;
DOI:10.1016/0223-5234(91)90121-3
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 95 percent / iPr2NEt / dimethylsulfoxide / 3 h / 80 °C
2: 70 percent / H2 / 5percent Pd/C / dioxane / Ambient temperature
3: H2NNH2*H2O / ethanol / 2 h / Heating
4: 68 percent / iPr2NEt / dimethylformamide / 48 h / Ambient temperature
With
hydrogen; hydrazine hydrate; N-ethyl-N,N-diisopropylamine;
palladium on activated charcoal;
In
1,4-dioxane; ethanol; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1016/0223-5234(91)90121-3
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 70 percent / H2 / 5percent Pd/C / dioxane / Ambient temperature
2: H2NNH2*H2O / ethanol / 2 h / Heating
3: 68 percent / iPr2NEt / dimethylformamide / 48 h / Ambient temperature
With
hydrogen; hydrazine hydrate; N-ethyl-N,N-diisopropylamine;
palladium on activated charcoal;
In
1,4-dioxane; ethanol; N,N-dimethyl-formamide;
DOI:10.1016/0223-5234(91)90121-3
