[Phenyl(thiophen-2-yl)methylidene]propanedial

Base Information

• Chemical Name: [Phenyl(thiophen-2-yl)methylidene]propanedial
• CAS No.: 84457-10-3
• Molecular Formula: C14H10O2S
• Molecular Weight: 242.298
• DSSTox Substance ID: DTXSID20510015
• Mol file: 84457-10-3.mol

Synonyms:84457-10-3;[Phenyl(thiophen-2-yl)methylidene]propanedial;DTXSID20510015

Chemical Property of [Phenyl(thiophen-2-yl)methylidene]propanedial

Chemical Property:

• XLogP3: 3.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 242.04015073
• Heavy Atom Count: 17
• Complexity: 306

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=C(C=O)C=O)C2=CC=CS2

Technology Process of [Phenyl(thiophen-2-yl)methylidene]propanedial

There total 2 articles about [Phenyl(thiophen-2-yl)methylidene]propanedial which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dichloro-phenyl-[2]thienyl-methane (102417-61-8) → phenyl-2-thienylmethylenemalonaldehyde (84457-10-3)

Guidance literature:

Multi-step reaction with 2 steps

1: AgClO₄, CaCO₃ / nitromethane

2: H₂O, HClO₄, NaCl

With perchloric acid; water; silver perchlorate; calcium carbonate; sodium chloride; In nitromethane;

DOI:10.1055/s-1982-29954

Reference yield:

C18H22N2S(2+)*2ClO4(1-) → phenyl-2-thienylmethylenemalonaldehyde (84457-10-3)

Guidance literature:

With perchloric acid; water; sodium chloride; Yield given;

DOI:10.1055/s-1982-29954

Reference yield: 95.0%

phenyl-2-thienylmethylenemalonaldehyde (84457-10-3) + methyl (triphenylphosphoranylidene)acetate (21204-67-1,2605-67-6) → (2E,4E)-4-Formyl-5-phenyl-5-thiophen-2-yl-penta-2,4-dienoic acid methyl ester

Guidance literature:

In benzene; at 25 ℃; for 60h;

DOI:10.1007/BF00951091

upstream raw materials:

dichloro-phenyl-[2]thienyl-methane

Downstream raw materials:

(2E,4Z)-4-Formyl-5-phenyl-5-thiophen-2-yl-penta-2,4-dienoic acid methyl ester

(2E,5E)-4-(Phenyl-thiophen-2-yl-methylene)-hepta-2,5-dienedioic acid dimethyl ester