4-(Chloromethyl)-5-hydroxy-2(5H)-furanone

Base Information

Chemical Name:4-(Chloromethyl)-5-hydroxy-2(5H)-furanone
CAS No.:125974-06-3
Molecular Formula:C₅H₅ClO₃
Molecular Weight:148.546
Hs Code.:
DSSTox Substance ID:DTXSID50925335
Nikkaji Number:J313.413J
Mol file:125974-06-3.mol

Synonyms:125974-06-3;4-(Chloromethyl)-5-hydroxy-2(5H)-furanone;3-(chloromethyl)-2-hydroxy-2H-furan-5-one;CCRIS 5362;UNII-0SA8W1M788;CGGKPVLGRJYRIP-UHFFFAOYSA-;DTXSID50925335;AKOS006280175;4-chloromethyl-5-hydroxy-2(5h)-furanone;4-(Chloromethyl)-5-hydroxyfuran-2(5H)-one;InChI=1/C5H5ClO3/c6-2-3-1-4(7)9-5(3)8/h1,5,8H,2H2

Suppliers and Price of 4-(Chloromethyl)-5-hydroxy-2(5H)-furanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
4-(chloromethyl)-5-hydroxy-2(5H)-Furanone 97.00%
5G
$ 3900.00

Total 1 raw suppliers

Chemical Property of 4-(Chloromethyl)-5-hydroxy-2(5H)-furanone

Chemical Property:

Vapor Pressure:7.67E-07mmHg at 25°C
Boiling Point:366°C at 760 mmHg
Flash Point:175.1°C
PSA：46.53000
Density:1.531g/cm³
LogP:0.02680
XLogP3:-0.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:147.9927217
Heavy Atom Count:9
Complexity:164

Purity/Quality:: 4-(chloromethyl)-5-hydroxy-2(5H)-Furanone 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C(OC1=O)O)CCl

Technology Process of 4-(Chloromethyl)-5-hydroxy-2(5H)-furanone

There total 5 articles about 4-(Chloromethyl)-5-hydroxy-2(5H)-furanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: C₁₄H₂₅ClO₃Si

: 125974-06-3
4-(chloromethyl)-5-hydroxy-2(5H)-furanone

Guidance literature:: With amberlyst-15; water; Ambient temperature;
DOI:10.1055/s-1998-1574

Reference yield: 52.0%

: 125974-02-9
5-Bromo-4-(chloromethyl)-2(5H)-furanone

: 125974-06-3
4-(chloromethyl)-5-hydroxy-2(5H)-furanone

Guidance literature:: With silver(I) acetate; In water; acetone; at 25 ℃; for 100h;
DOI:10.1021/jo00296a053

Reference yield:

: 80904-75-2
4-hydroxymethyl-5H-furan-2-one

: 125974-06-3
4-(chloromethyl)-5-hydroxy-2(5H)-furanone

Guidance literature:: Multi-step reaction with 3 steps

1: 8 percent / Ph₃P, CCl₄ / 72 h / 25 °C

2: 98 percent / NBS / CCl₄ / 0.5 h / Irradiation

3: 52 percent / silver acetate / acetone; H₂O / 100 h / 25 °C

With tetrachloromethane; N-Bromosuccinimide; silver(I) acetate; triphenylphosphine; In tetrachloromethane; water; acetone;
DOI:10.1021/jo00296a053