3-Methyl-7-methoxy-8-morpholinomethyl-4'-chloroflavone

Base Information

Chemical Name:3-Methyl-7-methoxy-8-morpholinomethyl-4'-chloroflavone
CAS No.:86073-64-5
Molecular Formula:C₂₂H₂₂ClNO₄
Molecular Weight:399.874
Hs Code.:
DSSTox Substance ID:DTXSID90235389
Wikidata:Q83117281

Synonyms:3-Methyl-7-methoxy-8-morpholinomethyl-4'-chloroflavone;BRN 6008491;86073-64-5;4H-1-Benzopyran-4-one, 2-(4-chlorophenyl)-7-methoxy-3-methyl-8-(4-morpholinylmethyl)-;2-(4-Chlorophenyl)-7-methoxy-3-methyl-8-(4-morpholinylmethyl)-4H-1-benzopyran-4-one;C22H22ClNO4;C22-H22-Cl-N-O4;DTXSID90235389;LS-39499

Suppliers and Price of 3-Methyl-7-methoxy-8-morpholinomethyl-4'-chloroflavone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 0 raw suppliers

Chemical Property of 3-Methyl-7-methoxy-8-morpholinomethyl-4'-chloroflavone

Chemical Property:

Vapor Pressure:3.96E-12mmHg at 25°C
Boiling Point:549.6°C at 760 mmHg
Flash Point:286.2°C
Density:1.287g/cm³
XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:399.1237359
Heavy Atom Count:28
Complexity:595

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(OC2=C(C1=O)C=CC(=C2CN3CCOCC3)OC)C4=CC=C(C=C4)Cl

Technology Process of 3-Methyl-7-methoxy-8-morpholinomethyl-4'-chloroflavone

There total 4 articles about 3-Methyl-7-methoxy-8-morpholinomethyl-4'-chloroflavone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 110-91-8,99108-56-2
morpholine

: 86073-67-8
3-Methyl-7-methoxy-8-chloromethyl-4'-chloroflavone

: 86073-64-5
3-Methyl-7-methoxy-8-morpholinomethyl-4'-chloroflavone

Guidance literature:: In benzene; for 48h; Ambient temperature;
DOI:10.1002/ardp.19833160507

Reference yield:

: 6270-44-6
2-hydroxy-4-methoxypropiophenone

: 86073-64-5
3-Methyl-7-methoxy-8-morpholinomethyl-4'-chloroflavone

Guidance literature:: Multi-step reaction with 3 steps

1: 60 percent / sodium p-chlorobenzoate / 8 h / 180 - 190 °C

2: 80 percent / HCl / acetic acid; aq. HCl / 5 h / 70 - 80 °C

3: 80 percent / benzene / 48 h / Ambient temperature

With hydrogenchloride; sodium p-chlorobenzoate; In hydrogenchloride; acetic acid; benzene;
DOI:10.1002/ardp.19833160507

Reference yield:

: 122-01-0
4-chloro-benzoyl chloride

: 86073-64-5
3-Methyl-7-methoxy-8-morpholinomethyl-4'-chloroflavone

Guidance literature:: Multi-step reaction with 3 steps

1: 60 percent / sodium p-chlorobenzoate / 8 h / 180 - 190 °C

2: 80 percent / HCl / acetic acid; aq. HCl / 5 h / 70 - 80 °C

3: 80 percent / benzene / 48 h / Ambient temperature

With hydrogenchloride; sodium p-chlorobenzoate; In hydrogenchloride; acetic acid; benzene;
DOI:10.1002/ardp.19833160507