1-(2-Hydroxyphenyl)-3-(4-nitrophenyl)propane-1,3-dione

Base Information

Chemical Name:1-(2-Hydroxyphenyl)-3-(4-nitrophenyl)propane-1,3-dione
CAS No.:84634-64-0
Molecular Formula:C15H11NO5
Molecular Weight:285.256
Hs Code.:
DSSTox Substance ID:DTXSID60408967
Nikkaji Number:J502.003D
Wikidata:Q82214594

Synonyms:1-(2-hydroxyphenyl)-3-(4-nitrophenyl)propane-1,3-dione;84634-64-0;DTXSID60408967;AKOS024362143

Suppliers and Price of 1-(2-Hydroxyphenyl)-3-(4-nitrophenyl)propane-1,3-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1-(2-Hydroxyphenyl)-3-(4-nitrophenyl)propane-1,3-dione

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:285.06372245
Heavy Atom Count:21
Complexity:409

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C(=O)CC(=O)C2=CC=C(C=C2)[N+](=O)[O-])O

Technology Process of 1-(2-Hydroxyphenyl)-3-(4-nitrophenyl)propane-1,3-dione

There total 9 articles about 1-(2-Hydroxyphenyl)-3-(4-nitrophenyl)propane-1,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 36695-15-5
1-[2-(4-nitrobenzoyloxy)-phenyl]-ethanone

: 84634-64-0
1-(2-hydroxy-phenyl)-3-(4-nitro-phenyl)-propane-1,3-dione

Guidance literature:: With potassium hydroxide; In pyridine; at 45 ℃; for 3h;

Reference yield:

: 118-93-4,104809-67-8
o-hydroxyacetophenone

: 122-04-3
4-nitro-benzoyl chloride

: 84634-64-0
1-(2-hydroxy-phenyl)-3-(4-nitro-phenyl)-propane-1,3-dione

Guidance literature:: With lithium hexamethyldisilazane; Multistep reaction; 1.) THF, 078 deg C, 2 h, 2.) THF, a) -78 deg C, 1 h, b) RT, 20 h;
DOI:10.1021/jm00046a020

Reference yield:

: 118-93-4,104809-67-8
o-hydroxyacetophenone

: 84634-64-0
1-(2-hydroxy-phenyl)-3-(4-nitro-phenyl)-propane-1,3-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 62 percent / POCl₂ / pyridine / 3 h / 60 - 70 °C

2: NaH / tetrahydrofuran / 3 h / Heating

With sodium hydride; In tetrahydrofuran; pyridine; 2: Baker-Venkataraman rearrangement;
DOI:10.1007/s00706-006-0550-9