Methyl 3-iodo-4-(2,2,2-trifluoroacetamido)benzoate

Base Information

Chemical Name:Methyl 3-iodo-4-(2,2,2-trifluoroacetamido)benzoate
CAS No.:848485-43-8
Molecular Formula:C10H7F3INO3
Molecular Weight:373.07
Hs Code.:
DSSTox Substance ID:DTXSID80467798
Nikkaji Number:J2.544.637B
Wikidata:Q82294869

Synonyms:METHYL 3-IODO-4-(2,2,2-TRIFLUOROACETAMIDO)BENZOATE;848485-43-8;Methyl 3-iodo-4-[(2,2,2-trifluoroacetyl)amino]benzoate;MFCD11501882;methyl 3-iodo-4-[(trifluoroacetyl)amino]benzoate;AR3371;SCHEMBL979300;DTXSID80467798;YIB48543;AKOS027255171;AS-45593;SY240751;CS-0091519;A914973;METHYL3-IODO-4-(2,2,2-TRIFLUOROACETAMIDO)BENZOATE;3-Iodo-4-(2,2,2-trifluoro-acetylamino)-benzoic acid methyl ester

Suppliers and Price of Methyl 3-iodo-4-(2,2,2-trifluoroacetamido)benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of Methyl 3-iodo-4-(2,2,2-trifluoroacetamido)benzoate

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:372.94228
Heavy Atom Count:18
Complexity:335

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C1=CC(=C(C=C1)NC(=O)C(F)(F)F)I

Technology Process of Methyl 3-iodo-4-(2,2,2-trifluoroacetamido)benzoate

There total 3 articles about Methyl 3-iodo-4-(2,2,2-trifluoroacetamido)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 19718-49-1
4-amino-3-iodobenzoic acid methyl ester

: 407-25-0
trifluoroacetic anhydride

: 848485-43-8
methyl 3-iodo-4-(2,2,2-trifluoroacetamido)benzoate

Guidance literature:: In tetrahydrofuran; at 0 ℃; for 0.166667h;
DOI:10.1021/jm049122i

Reference yield: 89.0%

: 14452-30-3
3'-iodoacetophenone

: 407-25-0
trifluoroacetic anhydride

: 848485-43-8
methyl 3-iodo-4-(2,2,2-trifluoroacetamido)benzoate

Guidance literature:: 3'-iodoacetophenone; trifluoroacetic anhydride; With pyridine; In dichloromethane; at 0 - 20 ℃;

With hydrogenchloride; In dichloromethane; water;

Reference yield:

: 619-45-4
4-methoxycarbonyl aniline

: 848485-43-8
methyl 3-iodo-4-(2,2,2-trifluoroacetamido)benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: N-iodo-succinimide / tetrahydrofuran / 20 °C

2: triethylamine / dichloromethane / 20 °C

With N-iodo-succinimide; triethylamine; In tetrahydrofuran; dichloromethane;