1-bromo-4-[6-(4-bromophenoxy)hexoxy]benzene

Base Information

• Chemical Name: 1-bromo-4-[6-(4-bromophenoxy)hexoxy]benzene
• CAS No.: 6943-11-9
• Molecular Formula: C18H20 Br2 O2
• Molecular Weight: 428.1582
• Hs Code.: 2909309090
• Mol file: 6943-11-9.mol

Synonyms:NSC 51642

Chemical Property of 1-bromo-4-[6-(4-bromophenoxy)hexoxy]benzene

Chemical Property:

• Boiling Point: 490.2oC at 760 mmHg
• Flash Point: 204.9oC
• PSA: 18.46000
• Density: 1.442g/cm3
• LogP: 6.22980

Purity/Quality:

99% ^*data from raw suppliers

1,6-Bis(4-bromophenoxy)hexane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-bromo-4-[6-(4-bromophenoxy)hexoxy]benzene

There total 1 articles about 1-bromo-4-[6-(4-bromophenoxy)hexoxy]benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

1 ,6-dibromohexane (629-03-8) + 4-bromo-phenol (106-41-2) → 1,6-bis(4-bromophenoxy)hexane (6943-11-9)

Guidance literature:

With potassium hydroxide; In butan-1-ol; Reflux;

Reference yield: 89.0%

2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (61676-62-8) + 1,6-bis(4-bromophenoxy)hexane (6943-11-9) → 1,6-bis(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)hexane

Guidance literature:

1,6-bis(4-bromophenoxy)hexane; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h; Inert atmosphere; Schlenk technique;

2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 4h; Inert atmosphere; Schlenk technique;

DOI:10.1002/chem.201800322

Reference yield: 70.0%

7-methoxy-1,3,5-cycloheptatriene (1714-38-1) + 1,6-bis(4-bromophenoxy)hexane (6943-11-9) → 1,6-bis[4-(cyclohepta-2,4,6-trien-1-yl)phenoxy]hexane (216307-11-8)

Guidance literature:

1,6-bis(4-bromophenoxy)hexane; With magnesium; In tetrahydrofuran;

7-methoxy-1,3,5-cycloheptatriene; In tetrahydrofuran; for 4h; Reflux;

upstream raw materials:

1 ,6-dibromohexane

4-bromo-phenol

Downstream raw materials:

4-(4-{6-[4-(3-Hydroxy-3-methyl-but-1-ynyl)-phenoxy]-hexyloxy}-phenyl)-2-methyl-but-3-yn-2-ol

1,6-bis(4-ethynylphenoxy)hexane

1,6-bis[4-(cyclohepta-2,4,6-trien-1-yl)phenoxy]hexane

1,6-bis{4-[3-(4-ethylaminophenyl)-cyclohepta-1,4,6-trien-1-yl]phenoxy}hexane

Refernces

• 1、 Hermann, Mathias,Wassy, Daniel,Kratzert, Daniel,Esser, Birgit. "Dibenzo[a,e]pentalenophanes: Bending a Non-Alternant Hydrocarbon". supporting information. p. 7374 - 7387. Retrieved 2018/05/04.
• 2、 Babirad, Stephan A.,Feld, William A.. "Synthesis of Acetylene-Terminated α,ω-Bisphenoxyalkanes". . p. 140 - 141. Retrieved 2007/10/02.