2-Acetamido-5-bromopyridine

Base Information

Chemical Name:2-Acetamido-5-bromopyridine
CAS No.:7169-97-3
Molecular Formula:C7H7 Br N2 O
Molecular Weight:215.049
Hs Code.:29339900
European Community (EC) Number:626-709-0
NSC Number:159406
DSSTox Substance ID:DTXSID80303622
Nikkaji Number:J454.766G
Wikidata:Q72434011
Mol file:7169-97-3.mol

Synonyms:7169-97-3;2-Acetamido-5-bromopyridine;n-(5-bromopyridin-2-yl)acetamide;2-Acetylamino-5-bromopyridine;Acetamide, N-(5-bromo-2-pyridinyl)-;N-(5-bromo-2-pyridyl)acetamide;N-(5-bromo-2-pyridinyl)acetamide;MFCD00468968;n-(5-bromo-pyridin-2-yl)-acetamide;2-Acetylamino-5-bromopyridine, 98%;N-ACETYLAMINO-5-BROMOPYRIDINE;NSC159406;SCHEMBL356367;N-(5-bromopyrid-2-yl)acetamide;DTXSID80303622;N-(5bromo-2-pyridinyl)acetamide;MJFCOXATGBYERZ-UHFFFAOYSA-N;n-(5-bromo-pyridin-2-yl)acetamide;N(5-Bromo-pyridin-2-yl)-acetamide;AKOS008979380;AC-6753;CCG-340061;DS-1877;FS-2283;NSC-159406;SY022132;A9378;AM20061462;FT-0647253;AC-907/34126032;A1-00386

Suppliers and Price of 2-Acetamido-5-bromopyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

A1 Biochem Labs
2-Acetamido-5-bromopyridine 97%
25 g
$ 100.00

Acrotein
N-(5-Bromo-pyridin-2-yl)acetamide 97%
25g
$ 140.62

Acrotein
N-(5-Bromo-pyridin-2-yl)acetamide 97%
100g
$ 443.30

AK Scientific
N-(5-Bromopyridin-2-yl)acetamide
1g
$ 63.00

Alfa Aesar
2-Acetamido-5-bromopyridine, 98%
10g
$ 80.80

Alfa Aesar
2-Acetamido-5-bromopyridine, 98%
1g
$ 20.60

Ambeed
N-(5-Bromopyridin-2-yl)acetamide 98%
1g
$ 9.00

Ambeed
N-(5-Bromopyridin-2-yl)acetamide 98%
5g
$ 26.00

Ambeed
N-(5-Bromopyridin-2-yl)acetamide 98%
10g
$ 51.00

Ambeed
N-(5-Bromopyridin-2-yl)acetamide 98%
25g
$ 95.00

Total 63 raw suppliers

Chemical Property of 2-Acetamido-5-bromopyridine

Chemical Property:

Vapor Pressure:9.8E-06mmHg at 25°C
Melting Point:175-179 °C (lit.)
Boiling Point:372.2°Cat760mmHg
PKA:12.94±0.70(Predicted)
Flash Point:178.9°C
Density:1.63g/cm³
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:213.97418
Heavy Atom Count:11
Complexity:151

Purity/Quality:

99%, ^*data from raw suppliers

2-Acetamido-5-bromopyridine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn,T
Statements: 22-36/37/38-43-40
Safety Statements: 26-36/37/39-22

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC(=O)NC1=NC=C(C=C1)Br
Uses 2-Acetamido-5-bromopyridine is a chemical reagent used in the synthesis of novel Bcr-Abl inhibitors with diacylated piperazine felxible linkers. Also used to produce hetero-monocyclic derivatives as even more potent inhibitors of BCR-ABL.

Technology Process of 2-Acetamido-5-bromopyridine

There total 1 articles about 2-Acetamido-5-bromopyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

: 1072-97-5
5-bromo-2-pyridylamine

: 104-15-4
toluene-4-sulfonic acid

: 5-bromo-2-(4-methylphenylsulfonyloxy)pyridine

: 7169-97-3
N-(5-bromopyridin-2-yl)acetamide

Guidance literature:: With toluene-4-sulfonic acid; potassium iodide; sodium nitrite; In acetonitrile; at 20 ℃;
DOI:10.1055/s-2006-958936

Reference yield: 76.0%

: 7169-97-3
N-(5-bromopyridin-2-yl)acetamide

: 14047-29-1
4-carboxyphenylboronic acid

: 4-[6-(acetylamino)pyridin-3-yl]benzoic acid

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; caesium carbonate; In methanol; acetonitrile; at 90 ℃; for 48h; Inert atmosphere;
DOI:10.1039/c5ob00430f

Reference yield: 76.0%

: 7169-97-3
N-(5-bromopyridin-2-yl)acetamide

: 586-76-5
4-Bromobenzoic acid

: 4-[6-(acetylamino)pyridin-3-yl]benzoic acid

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; caesium carbonate; In water; acetonitrile; at 90 ℃; for 48h; Inert atmosphere;
DOI:10.1016/j.bmc.2021.116398