Pro-Asp

Base Information

• Chemical Name: Pro-Asp
• CAS No.: 85227-98-1
• Molecular Formula: C₉H₁₄N₂O₅
• Molecular Weight: 230.221
• DSSTox Substance ID: DTXSID80397142
• Mol file: 85227-98-1.mol

Synonyms:Pro-Asp;prolylaspartic acid;2-(pyrrolidine-2-carbonylamino)butanedioic Acid;Prolyl-Aspartate;(S)-2-((S)-Pyrrolidine-2-carboxamido)succinic acid;Prolylaspartate;TL??4;PD dipeptide;P-D Dipeptide;L-Prolyl-L-Aspartate;Proline Aspartate dipeptide;Proline-Aspartate dipeptide;(2S)-2-[[(2S)-pyrrolidine-2-carbonyl]amino]butanedioic acid;DTXSID80397142;GLEOIKLQBZNKJZ-UHFFFAOYSA-N;AKOS020224623;FT-0772468

Chemical Property of Pro-Asp

Chemical Property:

• Vapor Pressure: 1.65E-11mmHg at 25°C
• Boiling Point: 503.6oC at 760 mmHg
• Flash Point: 258.4oC
• PSA: 119.22000
• Density: 1.404g/cm3
• LogP: -0.04840
• Storage Temp.: −20°C
• XLogP3: -4.6
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 5
• Exact Mass: 230.09027155
• Heavy Atom Count: 16
• Complexity: 304

Purity/Quality:

97% ^*data from raw suppliers

PRO-ASP-OH 98.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC(NC1)C(=O)NC(CC(=O)O)C(=O)O

Technology Process of Pro-Asp

There total 1 articles about Pro-Asp which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-Aspartic acid (56-84-8,25608-40-6,27881-03-4,32505-46-7,52526-39-3) + (S)-benzyloxycarbonyl-proline acid chloride (61350-60-5,61350-62-7,89705-40-8,106709-50-6) → prolyl‐aspartate (85227-98-1)

Guidance literature:

With sodium hydroxide; diethyl ether; Hydrieren des Reaktionsprodukts an Palladium in Methanol unter Zusatz von wss. Essigsaeure;

upstream raw materials:

L-Aspartic acid

(S)-benzyloxycarbonyl-proline acid chloride