Carbamic acid, (4-mercaptophenyl)-, 1,1-dimethylethyl ester

Base Information

• Chemical Name: Carbamic acid, (4-mercaptophenyl)-, 1,1-dimethylethyl ester
• CAS No.: 852448-31-8
• Molecular Formula: C11H15NO2S
• Molecular Weight: 225.312
• Mol file: 852448-31-8.mol

Synonyms:(4-Mercapto-phenyl)-carbamic acid tert-butyl ester;t-butyl N-(4-mercaptophenyl)carbamate;(4-mercaptophenyl)carbamic acid tert-butyl ester;4-mercaptophenylcarbamic acid tert-butyl ester;tert-butyl N-(4-mercaptophenyl)carbamate;4-mercaptophenyl-carbamic acid tert-butyl ester;tert-butyl (4-mercaptophenyl)carbamate;

Chemical Property of Carbamic acid, (4-mercaptophenyl)-, 1,1-dimethylethyl ester

Chemical Property:

• Melting Point: 179 - 180 °C
• Boiling Point: 288.2±23.0 °C(Predicted)
• PSA: 77.13000
• Density: 1.179±0.06 g/cm3(Predicted)
• LogP: 3.39530

Purity/Quality:

97% ^*data from raw suppliers

tert-butylN-(4-sulfanylphenyl)carbamate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Carbamic acid, (4-mercaptophenyl)-, 1,1-dimethylethyl ester

There total 3 articles about Carbamic acid, (4-mercaptophenyl)-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

di-tert-butyl dicarbonate (24424-99-5) + 4-aminotiophenol (1193-02-8) → (4-mercaptophenyl)carbamic acid tert-butyl ester (852448-31-8)

Guidance literature:

With indium(III) chloride; at 35 ℃; for 2h;

DOI:10.1021/jm801509w

Reference yield: 100.0%

→ (4-mercaptophenyl)carbamic acid tert-butyl ester (852448-31-8)

Guidance literature:

Reference yield: 91.0%

tert-butyl (3-cyano-4,6-dimethylpyridin-2-yl) carbonate + 4-aminotiophenol (1193-02-8) → (4-mercaptophenyl)carbamic acid tert-butyl ester (852448-31-8)

Guidance literature:

In ethanol; for 1h; Reflux;

DOI:10.1039/c9nj00885c

upstream raw materials:

di-tert-butyl dicarbonate

4-aminotiophenol

Downstream raw materials:

4-(pyridin-4-ylthio)aniline